Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MYLK | Q15746 | 4/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.33 |
| ▸ | AS3MT | Q9HBK9 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4375180 | 0.76 | PSEN1 (0.38) | ALDH1A1KDM4EMAPTHPGDTSHR | |
| SCHEMBL4055284 | 0.72 | CASP3 (0.36) | ALDH1A1KDM4EMAPTHPGDKMT2A | |
| SCHEMBL4052668 | 0.69 | MAPT (0.43) | ALDH1A1KDM4EMAPTHPGDMYLK | |
| SCHEMBL11821422 | 0.68 | CYP1A2 (0.48) | ALDH1A1KDM4EMAPTHPGDTSHR | |
| SCHEMBL11920949 | 0.67 | ALDH1A1 (0.39) | ALDH1A1KDM4EMAPTHPGDTSHR | |
| SCHEMBL4053047 | 0.67 | ALDH1A1 (0.39) | ALDH1A1MAPTMEN1KMT2ANPC1 | |
| SCHEMBL8021561 | 0.66 | ALDH1A1 (0.39) | ALDH1A1KDM4EMAPTHPGDTSHR | |
| SCHEMBL4239306 | 0.66 | POLB (0.34) | ALDH1A1KDM4EMAPTHPGDTSHR | |
| SCHEMBL4373655 | 0.65 | MEN1 (0.66) | ALDH1A1KDM4EMAPTHPGDTSHR | |
| SCHEMBL11093234 | 0.65 | ALDH1A1 (0.39) | ALDH1A1KDM4EMAPTHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009115874-A2 | NOVEL HETEROCYCLIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESSES FOR THEIR PREPARATION | MATRIX LABORATORIES LTD. (IN) | 2009-09-24 | — | — | WO | disclosed |