Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HK1 | P19367 | 1/20 | 0.33 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 3/20 | 0.33 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4053047 | 0.87 | ALDH1A1 (0.39) | PLA2G4AALDH1A1MAPTNPSR1TP53 | |
| SCHEMBL4375183 | 0.75 | KDM4E (0.37) | CASP3KDM4EPLA2G4AALDH1A1LMNA | |
| SCHEMBL4055280 | 0.72 | ALDH1A1 (0.35) | KDM4EALDH1A1HPGDMAPTHSD17B10 | |
| SCHEMBL4053668 | 0.71 | KDM4E (0.39) | KDM4EPLA2G4AALDH1A1HPGDLMNA | |
| SCHEMBL11822888 | 0.70 | HSD17B10 (0.46) | KDM4EALDH1A1HPGDLMNAMAPT | |
| SCHEMBL6623387 | 0.69 | KDM4E (0.44) | KDM4EALDH1A1HPGDLMNAMAPT | |
| SCHEMBL4052669 | 0.69 | KDM4E (0.41) | KDM4EPLA2G4AALDH1A1HPGDHSD17B10 | |
| SCHEMBL11821360 | 0.68 | CA12 (0.41) | KDM4EALDH1A1HPGDLMNAMAPT | |
| SCHEMBL11825374 | 0.68 | MAPT (0.37) | KDM4EALDH1A1HPGDLMNAMAPT | |
| SCHEMBL7375552 | 0.68 | HSD17B10 (0.64) | ALDH1A1MAPTHSD17B10CNR1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009115874-A2 | NOVEL HETEROCYCLIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESSES FOR THEIR PREPARATION | MATRIX LABORATORIES LTD. (IN) | 2009-09-24 | — | — | WO | disclosed |