Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 5/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4058267 | 0.92 | CYP2C19 (0.49) | CYP2C19HIF1AMAPTKMT2ACYP2D6 | |
| SCHEMBL13851677 | 0.86 | HIF1A (0.58) | CYP2C19HIF1AMAPTKMT2ACYP2D6 | |
| SCHEMBL28607003 | 0.83 | KIF11 (0.43) | CYP2C19MAPTKMT2ACYP2D6MEN1 | |
| SCHEMBL3233776 | 0.81 | CYP2C19 (0.45) | CYP2C19HIF1AMAPTKMT2ACYP2D6 | |
| SCHEMBL17064282 | 0.81 | MAPT (0.44) | CYP2C19HIF1AMAPTKMT2ACYP2D6 | |
| SCHEMBL2095353 | 0.80 | CYP3A4 (0.53) | CYP2C19HIF1AMAPTKMT2ACYP2D6 | |
| SCHEMBL5898545 | 0.79 | MAPT (0.43) | CYP2C19HIF1AMAPTKMT2ACYP2D6 | |
| SCHEMBL4795430 | 0.78 | MAPT (0.39) | CYP2C19HIF1AMAPTKMT2ACYP2D6 | |
| SCHEMBL13865463 | 0.76 | KIF11 (0.55) | MAPTKMT2AKIF11HTT | |
| SCHEMBL5571409 | 0.76 | CYP2C19 (0.48) | CYP2C19HIF1AMAPTKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3046560-A1 | STEM CELL MODULATION II | University of Canberra (AU) | 2016-07-27 | — | — | EP | disclosed |
| WO-2015039187-A1 | STEM CELL MODULATION II | UNIVERSITY OF CANBERRA (AU) | 2015-03-26 | — | — | WO | disclosed |
| US-7550473-B2 | Pyrimidine derivatives useful as inhibitors of PKC-theta | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2009-06-23 | — | — | US | disclosed |
| US-20050124640-A1 | Pyrimidine derivatives useful as inhibitors of PKC-theta | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2005-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050124640-A1 | Pyrimidine derivatives useful as inhibitors of PKC-theta | PRKCQ, PRKCZ, PRKCH | CYP2C19 1705/4885HIF1A 2021/4885MAPT 3633/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.