Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 3/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.39 |
| ▸ | ATR | Q13535 | 7/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.35 |
| ▸ | MTOR | P42345 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4050577 | 0.91 | IKBKB (0.39) | IKBKBGPR119ATRCHRM4MAPK1 | |
| SCHEMBL4049265 | 0.89 | GPR119 (0.52) | IKBKBGPR119MAPK1 | |
| SCHEMBL4543839 | 0.88 | GPR119 (0.41) | IKBKBGPR119ATRCHRM4MAPK1 | |
| SCHEMBL13690518 | 0.87 | HTR1A (0.38) | IKBKBATR | |
| SCHEMBL4047813 | 0.81 | GPR119 (0.52) | GPR119MAPK1 | |
| SCHEMBL4376355 | 0.78 | ATR (0.39) | GPR119ATRMAPK1PIK3CAMTOR | |
| SCHEMBL4050702 | 0.77 | GPR119 (0.46) | GPR119ATRCHRM4MTOR | |
| SCHEMBL3983198 | 0.77 | GPR119 (0.56) | IKBKBGPR119CHRM4 | |
| SCHEMBL4374631 | 0.76 | ITGB3 (0.40) | GPR119ATR | |
| SCHEMBL4057221 | 0.75 | GPR119 (0.53) | GPR119ATR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106561-A1 | PYRAZINE COMPOUNDS FOR TREATING GPR119 RELATED DISORDERS | BIOVITRUM AB (PUBL) (SE) | 2009-09-03 | — | — | WO | disclosed |