Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 9/20 | 0.42 |
| ▸ | ATR | Q13535 | 3/20 | 0.41 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | SCD | O00767 | 1/20 | 0.37 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.37 |
| ▸ | PRKDC | P78527 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.35 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4370431 | 0.91 | ATR (0.50) | GPR119MCHR1ATRBAZ2BATM | |
| SCHEMBL4056589 | 0.88 | ATR (0.40) | GPR119MCHR1ATRMTORMKNK1 | |
| SCHEMBL4050800 | 0.88 | ALDH1A1 (0.41) | GPR119MCHR1ATR | |
| SCHEMBL13690482 | 0.87 | GPR119 (0.63) | GPR119 | |
| SCHEMBL13690401 | 0.87 | GPR119 (0.48) | GPR119MCHR1ATR | |
| SCHEMBL4062791 | 0.86 | HTR1A (0.44) | GPR119ATR | |
| SCHEMBL4374631 | 0.85 | ITGB3 (0.40) | GPR119MCHR1ATR | |
| SCHEMBL4376368 | 0.85 | MKNK1 (0.46) | ATRKCNH2MKNK1MKNK2 | |
| SCHEMBL4370580 | 0.83 | ATR (0.34) | GPR119MCHR1ATRMKNK1MKNK2 | |
| SCHEMBL4060086 | 0.83 | RORC (0.46) | GPR119MCHR1ATRMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106561-A1 | PYRAZINE COMPOUNDS FOR TREATING GPR119 RELATED DISORDERS | BIOVITRUM AB (PUBL) (SE) | 2009-09-03 | — | — | WO | disclosed |