Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 2/20 | 0.40 |
| ▸ | NPY2R | P49146 | 1/20 | 0.40 |
| ▸ | CCR5 | P51681 | 7/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4059921 | 0.82 | GPR119 (0.45) | KDM4E | |
| SCHEMBL15538592 | 0.81 | RET (0.44) | SLC6A4KDM4ERET | |
| SCHEMBL4051573 | 0.81 | CCR5 (0.41) | NPY1RCCR5KDM4ETDP1 | |
| SCHEMBL15537567 | 0.75 | SIGMAR1 (0.43) | — | |
| SCHEMBL23012550 | 0.73 | PTGDR2 (0.48) | NPY1RCCR5SLC6A4RET | |
| SCHEMBL29964762 | 0.72 | CCR5 (0.53) | CCR5KDM4ETDP1 | |
| SCHEMBL15539056 | 0.71 | PTGDR2 (0.41) | NPY1RCCR5RET | |
| SCHEMBL14774644 | 0.70 | RIPK1 (0.43) | NPY1RNPY2RCCR5SLC6A4RIPK1 | |
| SCHEMBL29964698 | 0.70 | CCR5 (0.55) | NPY1RNPY2RCCR5SLC6A4RIPK1 | |
| SCHEMBL29366131 | 0.69 | HTR4 (0.40) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106565-A1 | AGONISTS OF GPR119 | BIOVITRUM AB (PUBL) (SE) | 2009-09-03 | — | — | WO | disclosed |