Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | ANPEP | P15144 | 2/20 | 0.47 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.47 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MME | P08473 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ACP3 | P15309 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6248066 | 1.00 | CNR2 (0.49) | CNR2TSHRKEAP1ANPEPERAP1 | |
| SCHEMBL5870056 | 1.00 | CNR2 (0.49) | CNR2TSHRKEAP1ANPEPERAP1 | |
| SCHEMBL11831098 | 0.89 | MMP12 (0.58) | TSHRMMEHTT | |
| SCHEMBL28160685 | 0.88 | GRIK1 (0.54) | KEAP1SMN1; SMN2PPARGPPARANPC1 | |
| SCHEMBL12222240 | 0.88 | GRIK1 (0.54) | KEAP1SMN1; SMN2PPARGPPARANPC1 | |
| SCHEMBL8472563 | 0.84 | ERAP1 (0.49) | CNR2TSHRKEAP1ANPEPERAP1 | |
| SCHEMBL27758940 | 0.82 | MMP12 (0.47) | ANPEPERAP1ERAP2SMN1; SMN2RAB9A | |
| SCHEMBL10518208 | 0.82 | ALDH1A1 (0.47) | TSHRANPEPPPARAMEN1KMT2A | |
| SCHEMBL11083245 | 0.82 | MDM2 (0.52) | CNR2TSHRKEAP1ANPEPERAP1 | |
| SCHEMBL2291948 | 0.80 | MMP8 (0.56) | CNR2TSHRKEAP1ANPEPERAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117305864-A | alpha-Fe 2 O 3 Porphyrin-based MOFs core-shell photoelectric catalyst and preparation method and application thereof | 石家庄铁道大学 | 2023-12-29 | — | — | CN | claimed |
| CN-107428092-B | Additive manufacturing method using photomodulated free radical polymerization | 陶氏环球技术有限责任公司 | 2021-06-08 | — | — | CN | claimed |
| EP-2033635-A1 | Short-chain fatty acid derivatives for treating pruritus | Asan Laboratories Company (Cayman) Limited (CN) | 2009-03-11 | — | — | EP | claimed |
| US-20080107646-A1 | Administering phenylbutyric acid derivative and pharmaceutically acceptable carrier | Sunny Pharmtech Inc. (TW) | 2008-05-08 | — | — | US | claimed |
| US-6403646-B1 | ADMINISTERING PHENYLBUTYRIC ACID OR DERIVATIVES TO TREAT LIVER DISEASE AND EMPHYSEMA CAUSED BY PROTEASE INHIBITOR TYPE Z MUTATION; STIMULATES SECRETION WITHOUT INCREASING SYNTHESIS OF PROTEIN | PERLMUTTER DAVID H (US) | 2002-06-11 | — | — | US | claimed |
| EP-0423133-B1 | ENZYMATIC RESOLUTION SYSTEMS AND COMPOUNDS USEFUL IN THE SYSTEMS AND THEIR REPARATIONS | SEPRACOR INC (US) | 1995-09-20 | — | — | EP | claimed |
| EP-0423133-A4 | ENZYMATIC RESOLUTION SYSTEMS AND COMPOUNDS USEFUL IN THE SYSTEMS AND THEIR REPARATIONS | — | 1992-04-15 | — | — | EP | claimed |
| US-5077217-A | Using enzymes in aqueous solutions | SEPRACOR, INC. (US) | 1991-12-31 | — | — | US | claimed |
| US-5057427-A | Enzymatic hydrolysis | SEPRACOR, INC. (US) | 1991-10-15 | — | — | US | claimed |
| EP-0423133-A1 | ENZYMATIC RESOLUTION SYSTEMS AND COMPOUNDS USEFUL IN THE SYSTEMS AND THEIR REPARATIONS. | SEPRACOR INC (US) | 1991-04-24 | — | — | EP | claimed |
| WO-1989009765-A1 | ENZYMATIC RESOLUTION SYSTEMS AND COMPOUNDS USEFUL IN THE SYSTEMS AND THEIR REPARATIONS | SEPRACOR, INC. (US) | 1989-10-19 | — | — | WO | claimed |
| CN-117305864-A | alpha-Fe 2 O 3 Porphyrin-based MOFs core-shell photoelectric catalyst and preparation method and application thereof | 石家庄铁道大学 | 2023-12-29 | — | — | CN | disclosed |
| EP-2935495-B1 | PRESSURE-SENSITIVE ADHESIVES PREPARED FROM DEGRADABLE MONOMERS AND POLYMERS | 3M INNOVATIVE PROPERTIES CO (US) | 2019-10-09 | — | — | EP | disclosed |
| US-9334428-B2 | Pressure-sensitive adhesives prepared from degradable monomers and polymers | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2016-05-10 | — | — | US | disclosed |
| CN-102753542-B | Substituted benzazepines as T0 LL-like receptor modulators | VENTIRX PHARMACEUTICALS, INC. (US) | 2016-01-20 | — | — | CN | disclosed |
| CN-85109243-A | Method for preparing antihypertensive octahydro-6-azaindole dipeptide derivative | — | 1986-09-17 | — | — | CN | disclosed |
| US-4532342-A | N-substituted amino acids as intermediates in the preparation of acyl derivatives of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids | WARNER-LAMBERT COMPANY (US) | 1985-07-30 | — | — | US | disclosed |
| US-4499102-A | HYPOTENSIVE AND ANTIDIABETIC AGENTS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1985-02-12 | — | — | US | disclosed |
| EP-0094095-A2 | Bicyclic carboxylic acids and their alkyl and aralkyl esters | F. HOFFMANN-LA ROCHE AG (CH) | 1983-11-16 | — | — | EP | disclosed |
| EP-0031104-A1 | Thiazolidine compounds, processes for their preparation and pharmaceutical compositions containing them | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1981-07-01 | — | — | EP | disclosed |