Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | ANPEP | P15144 | 2/20 | 0.47 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.47 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MME | P08473 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ACP3 | P15309 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4061138 | 1.00 | CNR2 (0.49) | CNR2TSHRKEAP1ANPEPERAP1 | |
| SCHEMBL5870056 | 1.00 | CNR2 (0.49) | CNR2TSHRKEAP1ANPEPERAP1 | |
| SCHEMBL11831098 | 0.89 | MMP12 (0.58) | TSHRMMEHTT | |
| SCHEMBL28160685 | 0.88 | GRIK1 (0.54) | KEAP1SMN1; SMN2PPARGPPARANPC1 | |
| SCHEMBL12222240 | 0.88 | GRIK1 (0.54) | KEAP1SMN1; SMN2PPARGPPARANPC1 | |
| SCHEMBL8472563 | 0.84 | ERAP1 (0.49) | CNR2TSHRKEAP1ANPEPERAP1 | |
| SCHEMBL27758940 | 0.82 | MMP12 (0.47) | ANPEPERAP1ERAP2SMN1; SMN2RAB9A | |
| SCHEMBL10518208 | 0.82 | ALDH1A1 (0.47) | TSHRANPEPPPARAMEN1KMT2A | |
| SCHEMBL11083245 | 0.82 | MDM2 (0.52) | CNR2TSHRKEAP1ANPEPERAP1 | |
| SCHEMBL2291948 | 0.80 | MMP8 (0.56) | CNR2TSHRKEAP1ANPEPERAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8540966-B2 | Contrast agents endowed with high relaxivity | BRACCO IMAGING S.P.A. (IT) | 2013-09-24 | — | — | US | disclosed |
| US-20110256067-A1 | Contrast agents endowed with high relaxivity | BRACCO IMAGING SPA (IT) | 2011-10-20 | — | — | US | disclosed |
| US-20110082280-A1 | Methods Of Coupling Multidentate AZA Ligands To Targeting Molecules | BRACCO IMAGING S.P.A. (IT) | 2011-04-07 | — | — | US | disclosed |
| WO-2005032541-A1 | SUBSTITUTED HETEROCYCLIC MERCAPTOSULFIDE INHIBITORS | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2005-04-14 | — | — | WO | disclosed |
| WO-2005032541-A1 | SUBSTITUTED HETEROCYCLIC MERCAPTOSULFIDE INHIBITORS | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2005-04-14 | — | — | WO | disclosed |
| EP-0728144-B1 | PEPTIDYL COMPOUNDS AND THEIR THERAPEUTIC USE AS INHIBITORS OF METALLOPROTEINASES | DARWIN DISCOVERY LTD (GB) | 2000-01-19 | — | — | EP | disclosed |
| US-5853623-A | Peptidyl compounds and their therapeutic use as inhibitors of metalloproteinases | CHIROSCIENCE LIMITED (GB) | 1998-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110256067-A1 | Contrast agents endowed with high relaxivity | SLC40A1, SLC67A1, SLC19A1 | CNR2 163/4885TSHR 1182/4885KEAP1 2061/4885 |
| US-20110082280-A1 | Methods Of Coupling Multidentate AZA Ligands To Targeting Molecules | CD99, CD209, PRMT9 | CNR2 3961/4885TSHR 10/4885KEAP1 4837/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.