Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20932207 | 0.84 | L3MBTL1 (0.53) | L3MBTL1ALDH1A1KDM4EGFERKMT2A | |
| SCHEMBL4060240 | 0.82 | ALDH1A1 (0.47) | L3MBTL1ALDH1A1KDM4EGFERKMT2A | |
| SCHEMBL16572388 | 0.81 | ALDH1A1 (0.68) | L3MBTL1ALDH1A1KDM4EGFERKMT2A | |
| SCHEMBL5510459 | 0.81 | ALDH1A1 (0.68) | L3MBTL1ALDH1A1KDM4EGFERKMT2A | |
| Hydrochloric Acid SCHEMBL11176717 | 0.81 | ALDH1A1 (0.49) | L3MBTL1ALDH1A1KDM4EGFERKMT2A | |
| SCHEMBL18284913 | 0.77 | MCHR1 (0.45) | L3MBTL1ALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL1203109 | 0.77 | CYP2D6 (0.46) | ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL11192385 | 0.76 | ABCB1 (0.58) | L3MBTL1ALDH1A1KDM4ESMN1; SMN2MAPK1 | |
| Hydrochloric Acid SCHEMBL11182664 | 0.75 | LMNA (0.60) | L3MBTL1ALDH1A1KDM4ESMN1; SMN2MAPK1 | |
| SCHEMBL12705234 | 0.74 | MCHR1 (0.41) | ALDH1A1KDM4EKMT2AMEN1MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009122180-A1 | PYRIMIDINE DERIVATIVES CAPABLE OF INHIBITING ONE OR MORE KINASES | MEDICAL RESEARCH COUNCIL (GB) | 2009-10-08 | — | — | WO | disclosed |