Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | PLA2G2C | Q5R387 | 7/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4067172 | 0.91 | THRB (0.39) | TSHRPLA2G2CTHRBALDH1A1 | |
| SCHEMBL4065864 | 0.84 | THRB (0.44) | TSHRTHRBALDH1A1CYP2C19 | |
| SCHEMBL4064266 | 0.80 | ALDH1A1 (0.45) | TSHRTHRBALDH1A1 | |
| SCHEMBL4060761 | 0.80 | TSHR (0.50) | TSHRPLA2G2CTHRBALDH1A1HPGD | |
| SCHEMBL7191777 | 0.80 | TSHR (0.46) | TSHRPLA2G2CTHRBALDH1A1CES2 | |
| SCHEMBL14330404 | 0.78 | TSHR (0.45) | TSHRPLA2G2CTHRBUSP2 | |
| SCHEMBL17629463 | 0.78 | LMNA (0.39) | PLA2G2CALDH1A1USP2ATMCYP1A2 | |
| SCHEMBL13641684 | 0.77 | TSHR (0.51) | TSHRPLA2G2CTHRBALDH1A1 | |
| SCHEMBL11111869 | 0.76 | TDP1 (0.44) | TSHRPLA2G2CTHRBALDH1A1CES2 | |
| SCHEMBL887703 | 0.76 | TDP1 (0.44) | TSHRPLA2G2CTHRBALDH1A1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009158302-A2 | VISCOUS ALPHA-CYANOACRYLATE COMPOSITIONS | CLOSURE MEDICAL CORPORATION (US) | 2009-12-30 | — | — | WO | claimed |
| WO-2009158302-A2 | VISCOUS ALPHA-CYANOACRYLATE COMPOSITIONS | CLOSURE MEDICAL CORPORATION (US) | 2009-12-30 | — | — | WO | disclosed |