SCHEMBL4063267

SCHEMBL4063267

Cc1cc(O)c(O)cc1C(c1ccc(C=O)cc1)c1cc(O)c(O)cc1C

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 2/20 0.44
PTGS2 P35354 2/20 0.44
RAB9A P51151 2/20 0.44
KDM4E B2RXH2 1/20 0.44
ALDH5A1 P51649 3/20 0.39
ABAT P80404 3/20 0.39
CYP2A6 P11509 1/20 0.39
ALDH1A1 P00352 3/20 0.38
AOX1 Q06278 1/20 0.38
TRIM24 O15164 1/20 0.38
HPGD P15428 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
TRIM33 Q9UPN9 1/20 0.38
PTGS1 P23219 2/20 0.36
TRPA1 O75762 1/20 0.34
CACNA1C Q13936 1/20 0.34
ALDH1A3 P47895 1/20 0.33
GUSB P08236 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29636363 0.92 TYR (0.43) TYRPTGS2RAB9AKDM4EALDH5A1
SCHEMBL283036 0.92 TYR (0.43) TYRPTGS2RAB9AKDM4EALDH5A1
SCHEMBL22039259 0.84 CYP2A6 (0.40) TYRPTGS2RAB9AKDM4EALDH5A1
SCHEMBL4055460 0.80 ESR1 (0.41) KDM4EALDH1A1HPGDTDP1PTGS1
SCHEMBL17557781 0.79 CYP2A6 (0.47) TYRPTGS2RAB9AKDM4EALDH5A1
SCHEMBL17557804 0.78 TYR (0.42) TYRPTGS2RAB9AKDM4EALDH5A1
SCHEMBL17557764 0.78 TYR (0.42) TYRPTGS2RAB9AKDM4EALDH5A1
SCHEMBL4060913 0.77 TYR (0.42) TYRKDM4EALDH1A1HPGDPTGS1
SCHEMBL278561 0.76 CYP2D6 (0.50) KDM4EALDH1A1HPGDTDP1PTGS1
SCHEMBL17557796 0.76 PTGS2 (0.49) TYRPTGS2RAB9AKDM4EALDH5A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7534547-B2 Optically active compound and photosensitive resin composition OSAKA GAS COMPANY LIMITED (JP) 2009-05-19 US disclosed
EP-1375463-A1 OPTICALLY ACTIVE COMPOUND AND PHOTOSENSITIVE RESIN COMPOSITION Kansai Research Institute, Inc. (JP) 2004-01-02 EP disclosed
US-20030211421-A1 Optically active compound and photosensitive resin composition KRI, INC. (JP) 2003-11-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030211421-A1 Optically active compound and photosensitive resin composition ARCN1, RAD51, PAM TYR 1522/4885PTGS2 1398/4885RAB9A 2005/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.