SCHEMBL4063699

SCHEMBL4063699

Cc1cc(O)ccc1Cc1cc(C(C)(C)c2cc(Cc3ccc(O)cc3C)c(O)c(Cc3ccc(O)cc3C)c2)cc(Cc2ccc(O)cc2C)c1O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 2/20 0.46
MAPK1 P28482 1/20 0.46
HTT P42858 1/20 0.46
HIF1A Q16665 3/20 0.41
CYP2C19 P33261 3/20 0.41
CYP2C9 P11712 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
HSD17B10 Q99714 3/20 0.41
CYP2D6 P10635 1/20 0.41
ESR1 P03372 6/20 0.39
ESR2 Q92731 6/20 0.39
CYP3A4 P08684 3/20 0.39
HPGD P15428 2/20 0.39
TSHR P16473 2/20 0.39
ESRRG P62508 2/20 0.39
AR P10275 1/20 0.39
SLC6A2 P23975 1/20 0.39
SLC6A4 P31645 1/20 0.39
HTR6 P50406 1/20 0.39
SLC6A3 Q01959 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4061811 0.95 ALOX15 (0.41) ALOX15MAPK1HTTHIF1ACYP2C19
SCHEMBL29852196 0.91 ESR1 (0.41) ALOX15MAPK1HTTHIF1ACYP2C19
SCHEMBL14462753 0.84 CYP2C19 (0.41) ALOX15HTTHIF1ACYP2C19CYP2C9
SCHEMBL4061742 0.82 AMY1A (0.56) HIF1ACYP2C19CYP2C9SMN1; SMN2HSD17B10
SCHEMBL4063293 0.82 AMY1A (0.56) HIF1ACYP2C19CYP2C9SMN1; SMN2HSD17B10
SCHEMBL30899196 0.82 ESR1 (0.38) ALOX15MAPK1HTTHSD17B10ESR1
SCHEMBL69172 0.82 ESR2 (0.49) ALOX15ESR1ESR2CYP3A4TSHR
SCHEMBL4063920 0.81 SHBG (0.43) HIF1ACYP2C19CYP2C9SMN1; SMN2HSD17B10
SCHEMBL2754942 0.78 ALOX15 (0.50) ALOX15MAPK1HTTHIF1ACYP2C19
SCHEMBL278512 0.78 ALOX15 (0.47) ALOX15MAPK1HTTHIF1ACYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7534547-B2 Optically active compound and photosensitive resin composition OSAKA GAS COMPANY LIMITED (JP) 2009-05-19 US disclosed
EP-1375463-A1 OPTICALLY ACTIVE COMPOUND AND PHOTOSENSITIVE RESIN COMPOSITION Kansai Research Institute, Inc. (JP) 2004-01-02 EP disclosed
US-20030211421-A1 Optically active compound and photosensitive resin composition KRI, INC. (JP) 2003-11-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030211421-A1 Optically active compound and photosensitive resin composition ARCN1, RAD51, PAM ALOX15 336/4885MAPK1 428/4885HTT 1421/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.