SCHEMBL278512

SCHEMBL278512

Cc1cc(Cc2cc(C(C)(C)c3cc(Cc4cc(C)c(O)cc4C)c(O)c(Cc4cc(C)c(O)cc4C)c3)cc(Cc3cc(C)c(O)cc3C)c2O)c(C)cc1O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 4/20 0.47
MAPK1 P28482 2/20 0.47
HTT P42858 1/20 0.47
HIF1A Q16665 5/20 0.45
CYP2C19 P33261 5/20 0.45
CYP2C9 P11712 4/20 0.45
HSD17B10 Q99714 3/20 0.45
CYP2D6 P10635 2/20 0.45
ESR1 P03372 3/20 0.44
SMN1; SMN2 Q16637 1/20 0.42
HSPA5 P11021 2/20 0.40
AMY1A P0DUB6 1/20 0.40
KLF10 Q13118 1/20 0.40
ALDH1A1 P00352 3/20 0.37
ALOX12 P18054 3/20 0.37
CYP3A4 P08684 2/20 0.37
HPGD P15428 2/20 0.37
TSHR P16473 1/20 0.37
CASP1 P29466 1/20 0.37
RECQL P46063 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29941774 0.82 AMY1A (0.58) ALOX15MAPK1HTTHIF1ACYP2C19
SCHEMBL13609020 0.82 AMY1A (0.58) ALOX15MAPK1HTTHIF1ACYP2C19
SCHEMBL30375265 0.82 AMY1A (0.58) ALOX15MAPK1HTTHIF1ACYP2C19
SCHEMBL278491 0.82 AMY1A (0.58) ALOX15MAPK1HTTHIF1ACYP2C19
SCHEMBL29713830 0.81 ALDH1A1 (0.52) ALOX15MAPK1HIF1ACYP2C19CYP2C9
SCHEMBL224889 0.81 ALDH1A1 (0.52) ALOX15MAPK1HIF1ACYP2C19CYP2C9
SCHEMBL4063126 0.80 SHBG (0.48) ALOX15MAPK1HIF1ACYP2C19CYP2C9
SCHEMBL2754942 0.80 ALOX15 (0.50) ALOX15MAPK1HTTHIF1ACYP2C19
SCHEMBL18121261 0.78 HIF1A (0.42) ALOX15MAPK1HTTHIF1ACYP2C19
SCHEMBL4063699 0.78 ALOX15 (0.46) ALOX15MAPK1HTTHIF1ACYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8530003-B2 Polybenzoxazole precursor, photosensitive resin composition using the same, and manufacturing method of semiconductor device FUJIFILM CORPORATION (JP) 2013-09-10 US disclosed
US-8530003-B2 Polybenzoxazole precursor, photosensitive resin composition using the same, and manufacturing method of semiconductor device FUJIFILM CORPORATION (JP) 2013-09-10 US disclosed
US-20120115333-A1 POLYBENZOXAZOLE PRECURSOR, PHOTOSENSITIVE RESIN COMPOSITION USING THE SAME, AND MANUFACTURING METHOD OF SEMICONDUCTOR DEVICE FUJIFILM CORPORATION (JP) 2012-05-10 US disclosed
US-8133550-B2 Good breaking elongation characteristics, achievable high sensitivity and high film remaining rate, little in pattern size fluctuation at the heating time after lithographic process, capable of stable pattern formation; manufacturing a semiconductor device FUJIFILM CORPORATION (JP) 2012-03-13 US disclosed
US-7534547-B2 Optically active compound and photosensitive resin composition OSAKA GAS COMPANY LIMITED (JP) 2009-05-19 US disclosed
US-20080076849-A1 POLYBENZOXAZOLE PRECURSOR, PHOTOSENSITIVE RESIN COMPOSITION USING THE SAME, AND MANUFACTURING METHOD OF SEMICONDUCTOR DEVICE FUJIFILM CORPORATION (JP) 2008-03-27 US disclosed
EP-1375463-A1 OPTICALLY ACTIVE COMPOUND AND PHOTOSENSITIVE RESIN COMPOSITION Kansai Research Institute, Inc. (JP) 2004-01-02 EP disclosed
US-20030211421-A1 Optically active compound and photosensitive resin composition KRI, INC. (JP) 2003-11-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120115333-A1 POLYBENZOXAZOLE PRECURSOR, PHOTOSENSITIVE RESIN COMPOSITION USING THE SAME, AND MANUFACTURING METHOD OF SEMICONDUCTOR DEVICE CD79B, BRIX1, SMARCB1 ALOX15 2591/4885MAPK1 3152/4885HTT 2882/4885
US-20030211421-A1 Optically active compound and photosensitive resin composition ARCN1, RAD51, PAM ALOX15 336/4885MAPK1 428/4885HTT 1421/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.