SCHEMBL406407

SCHEMBL406407

CC(C)C(=O)O.CCCC(C)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRR1 P24046 2/20 0.54
CYP1A2 P05177 1/20 0.54
ACE2 Q9BYF1 1/20 0.54
CHRM1 P11229 1/20 0.52
AKR1A1 P14550 1/20 0.52
CHRM3 P20309 1/20 0.52
HTR2A P28223 1/20 0.52
HTR2C P28335 1/20 0.52
ADRA1A P35348 1/20 0.52
HRH1 P35367 1/20 0.52
DRD3 P35462 1/20 0.52
SLC6A3 Q01959 1/20 0.52
HDAC1 Q13547 1/20 0.52
HDAC2 Q92769 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
BLM P54132 1/20 0.46
LTA4H P09960 1/20 0.42
GRIK1 P39086 1/20 0.40
SLC1A3 P43003 1/20 0.40
SLC1A2 P43004 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3136028 0.95
SCHEMBL5747303 0.95
SCHEMBL29281967 0.95 GABRR1 (0.59) GABRR1CYP1A2ACE2CHRM1AKR1A1
SCHEMBL148477 0.95
SCHEMBL17449760 0.95
Hydrochloric Acid SCHEMBL10884134 0.92
SCHEMBL18093480 0.92
SCHEMBL4861299 0.92
SCHEMBL22115933 0.92
SCHEMBL8411144 0.92

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120035308-A1 METHODS OF MAKING 6-HYDROXYHEXANOPHENONE AND 5-BENZOYLPENTANOIC ACID AND MONO OR DIESTERS THEREOF EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2012-02-09 US disclosed
US-20120022197-A2 PROCESS FOR MAKING MIXED TRIGLYCERIDE PLASTICIZER FROM BENZOIC AND TOLUIC ACID EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2012-01-26 US disclosed
US-20110257317-A1 TETRACARBOXYLIC ESTER PLASTICIZERS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2011-10-20 US disclosed
US-20110160371-A1 AROMATIC ACYLATION WITH CYCLIC ANHYDRIDE FOR PLASTICIZER PRODUCTION EXXONMOBILE RESEARCH AND ENGINEERING COMPANY (US) 2011-06-30 US disclosed
US-20110098390-A1 Process for Making Mixed Triglyceride Plasticizer From Benzoic and Toluic Acid EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2011-04-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110098390-A1 Process for Making Mixed Triglyceride Plasticizer From Benzoic and Toluic Acid GK, LIPA, LIPC GABRR1 2993/4885CYP1A2 683/4885ACE2 3682/4885
US-20110160371-A1 AROMATIC ACYLATION WITH CYCLIC ANHYDRIDE FOR PLASTICIZER PRODUCTION ACAD11, ACOT7, ACOX3 GABRR1 1902/4885CYP1A2 337/4885ACE2 1834/4885
US-20120035308-A1 METHODS OF MAKING 6-HYDROXYHEXANOPHENONE AND 5-BENZOYLPENTANOIC ACID AND MONO OR DIESTERS THEREOF HAAO, OXER1, CYP26B1 GABRR1 643/4885CYP1A2 78/4885ACE2 3213/4885
US-20110257317-A1 TETRACARBOXYLIC ESTER PLASTICIZERS ADH5, ADH1A, ADH1C GABRR1 3335/4885CYP1A2 214/4885ACE2 4186/4885
US-20120022197-A2 PROCESS FOR MAKING MIXED TRIGLYCERIDE PLASTICIZER FROM BENZOIC AND TOLUIC ACID GK, LIPA, LIPC GABRR1 2993/4885CYP1A2 683/4885ACE2 3682/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.