Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.34 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.34 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NPBWR1 | P48145 | 3/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.32 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7755931 | 0.77 | PKM (0.43) | MAPTALDH1A1KMT2ALMNANPSR1 | |
| SCHEMBL4064696 | 0.77 | HTT (0.46) | MAPTNPC1RAB9APAX8FGFR1 | |
| SCHEMBL5844822 | 0.75 | RAB9A (0.35) | MAPTTP53NPC1RAB9APAX8 | |
| SCHEMBL3342293 | 0.75 | HSD17B10 (0.34) | NPC1RAB9AKMT2AHTT | |
| SCHEMBL4062470 | 0.70 | NPBWR1 (0.42) | NPC1RAB9APAX8ALDH1A1KMT2A | |
| SCHEMBL3346925 | 0.68 | MAPT (0.42) | MAPTNPC1RAB9APAX8ALDH1A1 | |
| SCHEMBL3342417 | 0.68 | CA12 (0.38) | MAPTNPC1RAB9APAX8FGFR1 | |
| SCHEMBL29387767 | 0.66 | PPOX (0.63) | — | |
| SCHEMBL3195403 | 0.66 | PPOX (0.63) | — | |
| SCHEMBL10413922 | 0.66 | P2RX7 (0.34) | MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1070055-A1 | SUBSTITUTED PHENYL PYRIDAZINONES | Bayer Aktiengesellschaft (DE) | 2001-01-24 | — | — | EP | disclosed |
| WO-1999052878-A1 | SUBSTITUTED PHENYL PYRIDAZINONES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-10-21 | — | — | WO | disclosed |