Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PYGL | P06737 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.39 |
| ▸ | GOT1 | P17174 | 1/20 | 0.39 |
| ▸ | KYAT1 | Q16773 | 1/20 | 0.39 |
| ▸ | KYAT3 | Q6YP21 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4073287 | 0.88 | PYGL (0.39) | POLBPYGLALDH1A1TSHRAADAT | |
| SCHEMBL4064792 | 0.85 | AADAT (0.54) | POLBPYGLL3MBTL1AADATGOT1 | |
| SCHEMBL4066125 | 0.81 | LMNA (0.42) | POLBPYGLL3MBTL1ALDH1A1TSHR | |
| SCHEMBL4064970 | 0.79 | PYGL (0.44) | PYGLALDH1A1TSHRAADATGOT1 | |
| SCHEMBL4075040 | 0.79 | CHRM2 (0.54) | POLBALDH1A1TSHR | |
| SCHEMBL4075144 | 0.79 | CHRM2 (0.51) | POLBALDH1A1TSHR | |
| SCHEMBL4066622 | 0.79 | CHRM2 (0.46) | POLBALDH1A1TSHR | |
| SCHEMBL4064769 | 0.78 | PYGL (0.49) | PYGLALDH1A1TSHRAADATACE | |
| SCHEMBL4073069 | 0.78 | PYGL (0.47) | PYGLALDH1A1TSHRAADATGOT1 | |
| SCHEMBL4067884 | 0.77 | PYGL (0.50) | PYGLL3MBTL1ALDH1A1TSHRACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090099176-A1 | PYRROLOPYRIDINE-2-CARBOXYLIC ACID AMIDES | PROSIDION LIMITED (GB) | 2009-04-16 | — | — | US | disclosed |
| EP-1819332-B1 | PYRROLOPYRIDINE-2-CARBOXYLIC ACID AMIDES | PROSIDION LTD (GB) | 2009-03-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090099176-A1 | PYRROLOPYRIDINE-2-CARBOXYLIC ACID AMIDES | PC, GOT2, PDK1 | POLB 573/4885PYGL 104/4885L3MBTL1 3998/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.