Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 3/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | BCR | P11274 | 1/20 | 0.37 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4066534 | 0.95 | MRGPRX4 (0.40) | BRD4MRGPRX4GPR132ADRB2GRM5 | |
| SCHEMBL2966243 | 0.89 | KMT2A (0.43) | MRGPRX4ABL1GPR132KMT2AMEN1 | |
| SCHEMBL4072391 | 0.89 | MRGPRX4 (0.40) | MRGPRX4GPR132ADRB2GRM5FAAH | |
| SCHEMBL4068088 | 0.89 | FYN (0.40) | MRGPRX4GPR132GRM5 | |
| SCHEMBL4064790 | 0.88 | MRGPRX4 (0.39) | MRGPRX4ADRB2GRM5PDE2A | |
| SCHEMBL4073758 | 0.87 | MRGPRX4 (0.41) | MRGPRX4GPR132GRM5 | |
| SCHEMBL2973144 | 0.84 | HPGD (0.45) | MRGPRX4ABL1GPR132KMT2AMEN1 | |
| SCHEMBL4066415 | 0.83 | GPR132 (0.46) | GPR132ADRB2FAAH | |
| SCHEMBL4068787 | 0.81 | MRGPRX4 (0.40) | MRGPRX4ADRB2GRM5PDE2A | |
| SCHEMBL4072173 | 0.81 | ATM (0.40) | MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1658289-B1 | 3-SUBSTITUTED IMIDAZOPYRIDINE-DERIVATIVES AS C-KIT INHIBITORS | OSI PHARM INC (US) | 2009-03-18 | — | — | EP | claimed |