SCHEMBL4065843

SCHEMBL4065843

CCOC(C)Oc1ccc(C(c2ccc(OC(C)OCC)cc2)(C(F)(F)F)C(F)(F)F)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.37
ESR2 Q92731 1/20 0.37
LMNA P02545 6/20 0.35
PTPN5 P54829 1/20 0.35
FFAR1 O14842 2/20 0.33
PPARG P37231 2/20 0.33
SLC6A4 P31645 5/20 0.32
MEN1 O00255 5/20 0.32
KMT2A Q03164 5/20 0.32
SLC6A2 P23975 4/20 0.32
SLC6A3 Q01959 4/20 0.32
CYP3A4 P08684 3/20 0.32
HRH3 Q9Y5N1 2/20 0.32
NPC1 O15118 2/20 0.32
CYP2D6 P10635 2/20 0.32
CYP2C19 P33261 2/20 0.32
MTOR P42345 2/20 0.32
RAB9A P51151 2/20 0.32
HTR2C P28335 2/20 0.32
KCNK2 O95069 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13918193 0.83 PTPN5 (0.33) LMNAPTPN5FFAR1PPARGSLC6A4
SCHEMBL3852488 0.82 LMNA (0.52) LMNAKMT2ATSHRPPARAL3MBTL1
SCHEMBL4060025 0.81 NR1H4 (0.42) LMNAMEN1KMT2ANPC1RAB9A
SCHEMBL1456662 0.81 LMNA (0.39) ESR1ESR2LMNAPTPN5KMT2A
SCHEMBL196326 0.81 LMNA (0.39) ESR1ESR2LMNAPPARGSLC6A4
SCHEMBL825332 0.78 NPC1 (0.49) LMNAHRH3NPC1RAB9ACYP2C9
SCHEMBL12425736 0.78 LMNA (0.37) LMNANPC1RAB9AMAPT
SCHEMBL15869162 0.77 PSMB1 (0.36) ESR1ESR2LMNAPPARGSLC6A4
SCHEMBL4059616 0.76 LMNA (0.46) LMNAPTPN5PPARGCYP3A4CYP2D6
SCHEMBL13686333 0.76 MEN1 (0.36) LMNAPTPN5MEN1KMT2AMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7534547-B2 Optically active compound and photosensitive resin composition OSAKA GAS COMPANY LIMITED (JP) 2009-05-19 US disclosed
US-7534547-B2 Optically active compound and photosensitive resin composition OSAKA GAS COMPANY LIMITED (JP) 2009-05-19 US disclosed
EP-1375463-A1 OPTICALLY ACTIVE COMPOUND AND PHOTOSENSITIVE RESIN COMPOSITION Kansai Research Institute, Inc. (JP) 2004-01-02 EP disclosed
US-20030211421-A1 Optically active compound and photosensitive resin composition KRI, INC. (JP) 2003-11-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030211421-A1 Optically active compound and photosensitive resin composition ARCN1, RAD51, PAM ESR1 392/4885ESR2 895/4885LMNA 202/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.