SCHEMBL4066875

SCHEMBL4066875

CC[Si](CC)(CC)N1CCN(CCC[Si](OC)(OC)OC)CC1

nearest known ligand 0.32

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 1/20 0.32
DRD3 P35462 1/20 0.32
LMNA P02545 1/20 0.32
HTR1A P08908 1/20 0.31
MAPT P10636 1/20 0.31
GNAI3 P08754 1/20 0.30
GNAO1 P09471 1/20 0.30
GNAI1 P63096 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4069941 0.95 HTR1A (0.33) DRD2DRD3LMNAHTR1AMAPT
SCHEMBL4060191 0.89 DRD2 (0.30) DRD2
SCHEMBL4361438 0.85 MAPT (0.37) DRD2DRD3LMNAHTR1AMAPT
SCHEMBL11897301 0.85 MAPT (0.37) DRD2DRD3LMNAHTR1AMAPT
SCHEMBL4059963 0.85 CSNK2A2 (0.31)
SCHEMBL4062174 0.85 CSNK2A2 (0.31)
SCHEMBL4066930 0.85
SCHEMBL4062217 0.82 CSNK2A2 (0.33) DRD2DRD3LMNAMAPT
SCHEMBL14101115 0.82 MAPK1 (0.38) DRD2DRD3LMNAHTR1A
SCHEMBL31374750 0.82 DRD2 (0.45) DRD2DRD3LMNAHTR1AGNAI3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7569691-B2 Protected piperazino group-bearing organoxysilane compound and making method SHIN-ETSU CHEMICAL CO., LTD. (JP) 2009-08-04 US claimed
US-20260055216-A1 Conjugated Diene-Based Polymer, Formed Body, Production Method for Conjugated Diene-Based Polymer, Rubber Composition, and Tire ASAHI KASEI KABUSHIKI KAISHA (JP) 2026-02-26 US disclosed
CN-119497723-A Conjugated diene polymer, molded article, method for producing conjugated diene polymer, rubber composition, and tire 旭化成株式会社 2025-02-21 CN disclosed
US-7569691-B2 Protected piperazino group-bearing organoxysilane compound and making method SHIN-ETSU CHEMICAL CO., LTD. (JP) 2009-08-04 US disclosed
EP-1714968-B1 Protected piperazino group-bearing organoxysilane compound and making method SHINETSU CHEMICAL CO (JP) 2008-07-16 EP disclosed
US-20060241294-A1 Protected piperazino group-bearing organoxysilane compound and making method SHIN-ETSU CHEMICAL CO., LTD. 2006-10-26 US disclosed
EP-1714968-A1 Protected piperazino group-bearing organoxysilane compound and making method Shin-Etsu Chemical Co., Ltd. (JP) 2006-10-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260055216-A1 Conjugated Diene-Based Polymer, Formed Body, Production Method for Conjugated Diene-Based Polymer, Rubber Composition, and Tire HMGB2, HMGB1, HMGB3 DRD2 1369/4885DRD3 1082/4885LMNA 1042/4885
US-20060241294-A1 Protected piperazino group-bearing organoxysilane compound and making method PIEZO1, VCL, VIM DRD2 2063/4885DRD3 2220/4885LMNA 1225/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.