Trifluoromethanesulfonic Acid

Trifluoromethanesulfonic Acid

SCHEMBL3143626

COc1ccc([S+](c2ccccc2)c2ccc(OC)cc2)cc1.O=S(=O)([O-])C(F)(F)F

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 1/20 0.46
GAA P10253 1/20 0.43
KMT2A Q03164 1/20 0.43
PKM P14618 1/20 0.42
ACHE P22303 3/20 0.40
ALDH1A1 P00352 3/20 0.40
KEAP1 Q14145 1/20 0.40
CA4 P22748 1/20 0.39
PGR P06401 2/20 0.39
HSD11B1 P28845 1/20 0.39
GPR3 P46089 1/20 0.39
LTA4H P09960 1/20 0.39
HTT P42858 1/20 0.39
POLB P06746 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoromethanesulfonic Acid SCHEMBL36492 1.00 KCNH2 (0.46) KCNH2GAAKMT2APKMACHE
Trifluoromethanesulfonic Acid SCHEMBL31720833 0.94 KCNH2 (0.43) KCNH2GAAKMT2APKMACHE
Trifluoromethanesulfonic Acid SCHEMBL2324715 0.94 KCNH2 (0.43) KCNH2GAAKMT2APKMACHE
Trifluoromethanesulfonic Acid SCHEMBL454992 0.94 PKM (0.47) KCNH2GAAKMT2APKMACHE
Trifluoromethanesulfonic Acid SCHEMBL31720793 0.93 KCNH2 (0.42) KCNH2GAAKMT2APKMACHE
Trifluoromethanesulfonic Acid SCHEMBL31720636 0.89 APP (0.43) KCNH2GAAKMT2AALDH1A1HTT
Trifluoromethanesulfonic Acid SCHEMBL17536703 0.88 KCNH2 (0.39) KCNH2GAAKMT2AACHEALDH1A1
Trifluoromethanesulfonic Acid SCHEMBL31720772 0.88 KEAP1 (0.43) KCNH2GAAKMT2APKMACHE
Trifluoromethanesulfonic Acid SCHEMBL2901812 0.88 ACHE (0.47) KCNH2KMT2APKMACHEALDH1A1
Trifluoromethanesulfonic Acid SCHEMBL756009 0.88 CES2 (0.41) GAAKMT2APKMALDH1A1CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1676835-B1 PROCESS FOR PRODUCING TRIARYLSULFONIUM SALT WAKO PURE CHEM IND LTD (JP) 2014-12-10 EP disclosed
US-7642368-B2 for use as acid generator in semiconductor manufacture; triarylsulfonium salt having a structure that only one aromatic ring of three is different, in a high yield and by-product inhibition; reacting a diaryl sulfoxide with an aryl Grignard reagent in presence of chlorotrialkylsilane and strong acid WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2010-01-05 US disclosed
US-7323284-B2 Negative type radiation sensitive resin composition JSR CORPORATION (JP) 2008-01-29 US disclosed
US-20070083060-A1 for use as acid generator in semiconductor manufacture; triarylsulfonium salt having a structure that only one aromatic ring of three is different, in a high yield and by-product inhibition; reacting a diaryl sulfoxide with an aryl Grignard reagent in presence of chlorotrialkylsilane and strong acid FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2007-04-12 US disclosed
EP-1676835-A1 PROCESS FOR PRODUCING TRIARYLSULFONIUM SALT Wako Pure Chemical Industries, Ltd. (JP) 2006-07-05 EP disclosed
US-20030022095-A1 Negative type radiation sensitive resin composition JSR CORPORATION (JP) 2003-01-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070083060-A1 for use as acid generator in semiconductor manufacture; triarylsulfonium salt having a structure that only one aromatic ring of three is different, in a high yield and by-product inhibition; reacting a diaryl sulfoxide with an aryl Grignard reagent in presence of chlorotrialkylsilane and strong acid ARSA, HAO2, HAO1 KCNH2 479/4885GAA 972/4885KMT2A 833/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.