Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 9/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13748854 | 0.98 | SLC6A9 (0.43) | SLC6A9HTTNPSR1KCNH2KDM4E | |
| SCHEMBL13748066 | 0.93 | SLC6A9 (0.43) | SLC6A9NPSR1KCNH2KDM4EALDH1A1 | |
| SCHEMBL13748637 | 0.92 | SLC6A9 (0.43) | SLC6A9NPSR1KCNH2KDM4EALDH1A1 | |
| SCHEMBL13748776 | 0.92 | SLC6A9 (0.43) | SLC6A9NPSR1KCNH2KDM4EALDH1A1 | |
| SCHEMBL13748663 | 0.90 | KDM4E (0.44) | SLC6A9KCNH2KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL13749074 | 0.90 | SLC6A9 (0.42) | SLC6A9NPSR1KCNH2KDM4EALDH1A1 | |
| SCHEMBL13748544 | 0.88 | SLC6A9 (0.42) | SLC6A9NPSR1KCNH2KDM4EALDH1A1 | |
| SCHEMBL4069491 | 0.88 | HTT (0.39) | SLC6A9HTTNPSR1KDM4EALDH1A1 | |
| SCHEMBL4061339 | 0.88 | HRH3 (0.37) | SLC6A9HTTNPSR1KCNH2KDM4E | |
| SCHEMBL13749068 | 0.87 | CYP2C9 (0.38) | SLC6A9HTTNPSR1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009100120-A2 | PYRIDINYL-SUBSTITUTED PIPERAZINYL OXOETHYL TETRAHYDROPYRAZOLOPYRIDINES | NEUROGEN CORPORATION (US) | 2009-08-13 | — | — | WO | disclosed |
| WO-2009100120-A2 | PYRIDINYL-SUBSTITUTED PIPERAZINYL OXOETHYL TETRAHYDROPYRAZOLOPYRIDINES | NEUROGEN CORPORATION (US) | 2009-08-13 | — | — | WO | disclosed |