Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | CASP1 | P29466 | 3/20 | 0.33 |
| ▸ | CASP7 | P55210 | 3/20 | 0.33 |
| ▸ | GLA | P06280 | 2/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 6/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4065218 | 0.85 | ADORA1 (0.36) | KDM4EHPGDHSD17B10USP2TLR7 | |
| SCHEMBL6737901 | 0.64 | ELANE (0.40) | KDM4ETLR7GAAGLADPP4 | |
| SCHEMBL6221678 | 0.64 | DPP4 (0.40) | KDM4EHPGDALDH1A1DPP4PDE3B | |
| SCHEMBL8852871 | 0.63 | DYRK1A (0.52) | KDM4EHPGDHSD17B10ALDH1A1PDE3B | |
| Hydrochloric Acid SCHEMBL10970517 | 0.61 | MAOB (0.50) | HPGDMAPTCYP2D6CYP2C9CYP2C19 | |
| SCHEMBL1405835 | 0.61 | ALDH1A1 (0.47) | KDM4EHPGDHSD17B10USP2ALDH1A1 | |
| SCHEMBL4530714 | 0.60 | CYP1A2 (0.48) | HSD17B10GAARAD52CYP1A2CYP2D6 | |
| SCHEMBL7133357 | 0.60 | HTR2A (0.43) | KDM4EHPGDHSD17B10USP2ESR1 | |
| SCHEMBL5032885 | 0.59 | ELANE (0.43) | TLR7DPP4ALOX15PARP1 | |
| SCHEMBL20314907 | 0.59 | ESR2 (0.40) | ALDH1A1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1658076-A4 | ARYLOXY AND ARYLALKYLENEOXY SUBSTITUTED IMIDAZOQUINOLINES | 3M INNOVATIVE PROPERTIES CO (US) | 2009-02-25 | — | — | EP | disclosed |
| EP-1658076-A1 | ARYLOXY AND ARYLALKYLENEOXY SUBSTITUTED IMIDAZOQUINOLINES | 3M Innovative Properties Company (US) | 2006-05-24 | — | — | EP | disclosed |
| WO-2005020999-A1 | ARYLOXY AND ARYLALKYLENEOXY SUBSTITUTED IMIDAZOQUINOLINES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2005-03-10 | — | — | WO | disclosed |