Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 10/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.52 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.45 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | OGA | O60502 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4067477 | 0.86 | PDK2 (0.47) | SLC6A9KCNH2PDK2 | |
| SCHEMBL4063883 | 0.85 | MAPT (0.48) | SLC6A9KCNH2PDK2F10 | |
| SCHEMBL13749198 | 0.83 | SLC6A9 (0.45) | SLC6A9KCNH2PDK2F10 | |
| Hydrochloric Acid SCHEMBL4067798 | 0.82 | SLC6A9 (0.44) | SLC6A9KCNH2PDK2F10 | |
| SCHEMBL14861471 | 0.80 | PDK2 (0.52) | SLC6A9PDK2OGA | |
| SCHEMBL13748459 | 0.78 | SLC6A9 (0.44) | SLC6A9KCNH2PDK2F10CHRM4 | |
| SCHEMBL13749100 | 0.78 | SLC6A9 (0.42) | SLC6A9KCNH2PDK2CHRM4 | |
| SCHEMBL13748331 | 0.77 | ALDH1A1 (0.47) | SLC6A9KCNH2 | |
| SCHEMBL4070973 | 0.77 | SLC6A9 (0.44) | SLC6A9KCNH2PDK2RXRAGRIN1 | |
| SCHEMBL18131939 | 0.76 | PDK2 (0.44) | SLC6A9PDK2OGA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009100120-A2 | PYRIDINYL-SUBSTITUTED PIPERAZINYL OXOETHYL TETRAHYDROPYRAZOLOPYRIDINES | NEUROGEN CORPORATION (US) | 2009-08-13 | — | — | WO | disclosed |