Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 9/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.38 |
| ▸ | CDK9 | P50750 | 4/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | WNT3A | P56704 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13749198 | 0.87 | SLC6A9 (0.45) | SLC6A9KCNH2PDK2 | |
| Hydrochloric Acid SCHEMBL4067798 | 0.86 | SLC6A9 (0.44) | SLC6A9KCNH2PDK2 | |
| SCHEMBL4063883 | 0.84 | MAPT (0.48) | SLC6A9KCNH2PDK2MAPT | |
| SCHEMBL13749100 | 0.81 | SLC6A9 (0.42) | SLC6A9KCNH2PDK2KDM4EMEN1 | |
| SCHEMBL13748459 | 0.81 | SLC6A9 (0.44) | SLC6A9KCNH2PDK2KDM4EMEN1 | |
| SCHEMBL13748801 | 0.79 | SLC6A9 (0.41) | SLC6A9KCNH2PDK2KDM4EMEN1 | |
| SCHEMBL13748458 | 0.79 | SLC6A9 (0.44) | SLC6A9KCNH2PDK2CDK9KDM4E | |
| SCHEMBL13749073 | 0.79 | SLC6A9 (0.39) | SLC6A9KCNH2PDK2 | |
| SCHEMBL13748331 | 0.79 | ALDH1A1 (0.47) | SLC6A9KCNH2MEN1ALDH1A1MAPT | |
| SCHEMBL13749141 | 0.79 | SLC6A9 (0.43) | SLC6A9KCNH2PDK2KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009100120-A2 | PYRIDINYL-SUBSTITUTED PIPERAZINYL OXOETHYL TETRAHYDROPYRAZOLOPYRIDINES | NEUROGEN CORPORATION (US) | 2009-08-13 | — | — | WO | disclosed |
| WO-2009100120-A2 | PYRIDINYL-SUBSTITUTED PIPERAZINYL OXOETHYL TETRAHYDROPYRAZOLOPYRIDINES | NEUROGEN CORPORATION (US) | 2009-08-13 | — | — | WO | disclosed |