Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 11/20 | 0.52 |
| ▸ | CES1 | P23141 | 7/20 | 0.50 |
| ▸ | CES2 | O00748 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8167972 | 0.83 | FAAH (0.64) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL16140001 | 0.78 | FAAH (0.48) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL16789735 | 0.75 | CES2 (0.57) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL6266280 | 0.74 | ALDH1A1 (0.46) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL17461626 | 0.74 | ALDH1A1 (0.39) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL25263210 | 0.74 | ALDH1A1 (0.50) | KMT2AHSD17B10ALDH1A1TSHR | |
| SCHEMBL810081 | 0.74 | — | — | |
| SCHEMBL9937107 | 0.73 | ALDH1A1 (0.56) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL19501018 | 0.73 | FAAH (0.43) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL3603910 | 0.73 | FAAH (0.48) | FAAHCES1CES2MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3902786-B1 | PREPARATION OF SULFONAMIDE HERBICIDE PROCESS INTERMEDIATES | CORTEVA AGRISCIENCE LLC (US) | 2022-12-14 | — | — | EP | disclosed |
| EP-2866563-B1 | INSECTICIDAL N-SUBSTITUTED SULFILIMINE AND SULFOXIMINE PYRIDINE N-OXIDES | DOW AGROSCIENCES LLC (US) | 2019-07-31 | — | — | EP | disclosed |
| EP-2799913-B1 | OPTICAL MEMBER SET AND SOLID-STATE IMAGE SENSOR USING SAME | FUJIFILM CORP (JP) | 2017-02-01 | — | — | EP | disclosed |
| US-20160368876-A1 | METHOD FOR PREPARATION OF 6-TRIFLUOROMETHYLPYRIDINE-3-CARBOXYLIC ACID DERIVATIVES FROM TRIFLUOROACETYLACETIC ACID | LONZA LTD. (CH) | 2016-12-22 | — | — | US | disclosed |
| US-9522885-B1 | Method for preparation of 6-trifluoromethylpyridine-3-carboxylic acid derivatives from trifluoroacetylacetic acid | LONZA LTD (CH) | 2016-12-20 | — | — | US | disclosed |
| EP-2997014-B1 | METHOD FOR PREPARATION OF 6-TRIFLUOROMETHYLPYRIDINE-3-CARBOXYLIC ACID DERIVATIVES FROM TRIFLUOROACETYLACETIC ACID | LONZA AG (CH) | 2016-09-21 | — | — | EP | disclosed |
| EP-2997014-A1 | METHOD FOR PREPARATION OF 6-TRIFLUOROMETHYLPYRIDINE-3-CARBOXYLIC ACID DERIVATIVES FROM TRIFLUOROACETYLACETIC ACID | Lonza Ltd (CH) | 2016-03-23 | — | — | EP | disclosed |
| US-8957254-B2 | Process for chemical synthesis from an alkenone made from a halogenated precursor | SOLVAY SA (BE) | 2015-02-17 | — | — | US | disclosed |
| WO-2015007837-A1 | METHOD FOR PREPARATION OF 6-TRIFLUOROMETHYLPYRIDINE-3-CARBOXYLIC ACID DERIVATIVES FROM TRIFLUOROACETYLACETIC ACID | LONZA LTD (CH) | 2015-01-22 | — | — | WO | disclosed |
| US-20140051892-A1 | Process for chemical synthesis from an alkenone made from a halogenated precursor | SOLVAY SA (BE) | 2014-02-20 | — | — | US | disclosed |
| US-7488824-B2 | Process for the production of substituted nicotinic acid esters | SYNGENTA CROP PROTECTION, INC. (US) | 2009-02-10 | — | — | US | disclosed |
| EP-1601653-B1 | PROCESS FOR THE PRODUCTION OF SUBSTITUTED NICOTINIC ACID ESTERS | SYNGENTA PARTICIPATIONS AG (CH) | 2009-02-04 | — | — | EP | disclosed |
| US-20060199964-A1 | Process for the production of substituted nicotinic acid esters | SYNGENTA CROP PROTECTION, INC. | 2006-09-07 | — | — | US | disclosed |
| EP-0290903-A2 | Beta-fluoracyl-beta-halogen vinyl alkyl ethers | BAYER AG (DE) | 1988-11-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160368876-A1 | METHOD FOR PREPARATION OF 6-TRIFLUOROMETHYLPYRIDINE-3-CARBOXYLIC ACID DERIVATIVES FROM TRIFLUOROACETYLACETIC ACID | CYP2A6, CYP2B6, HPD | FAAH 128/4885CES1 42/4885CES2 53/4885 |
| US-20060199964-A1 | Process for the production of substituted nicotinic acid esters | CHRM1, CHRM5, CHRNA5 | FAAH 331/4885CES1 180/4885CES2 509/4885 |
| US-20140051892-A1 | Process for chemical synthesis from an alkenone made from a halogenated precursor | ALK, CYP4A11, SQLE | FAAH 44/4885CES1 1990/4885CES2 2855/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.