SCHEMBL4070717

SCHEMBL4070717

OCC(O)c1[c]cccc1

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.31
KDM4E B2RXH2 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28166688 1.00 LMNA (0.31) LMNAKDM4EL3MBTL1
SCHEMBL28166447 1.00 LMNA (0.31) LMNAKDM4EL3MBTL1
SCHEMBL14764013 0.83 TRPA1 (0.32)
SCHEMBL22363023 0.81 LMNA (0.30) LMNA
SCHEMBL3589887 0.81 LMNA (0.48) LMNA
SCHEMBL1145144 0.79 ALPI (0.42)
SCHEMBL7030565 0.79 ALOX5 (0.33)
SCHEMBL158756 0.78 LMNA (0.36) LMNAKDM4E
SCHEMBL21750403 0.78 HRH1 (0.38)
SCHEMBL3598843 0.78 AOC3 (0.33) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1313561-B1 SUPPORTED CATALYST BOREALIS TECH OY (FI) 2006-04-05 EP claimed
US-6982238-B2 Supported catalyst BOREALIS TECHNOLOGY OY (FI) 2006-01-03 US claimed
US-6887818-B2 Supported titanium catalyst system BOREALIS TECHNOLOGY OY (FI) 2005-05-03 US claimed
US-20040014912-A1 Supported titanium catalyst system BOREALIS TECHNOLOGY OY (FI) 2004-01-22 US claimed
US-20030166460-A1 Supported catalyst BOREALIS TECHNOLOGY OY (FI) 2003-09-04 US claimed
EP-1322676-A2 SUPPORTED TITANIUM CATALYST SYSTEM Borealis Technology Oy (FI) 2003-07-02 EP claimed
EP-1313561-A1 SUPPORTED CATALYST Borealis Technology Oy (FI) 2003-05-28 EP claimed
WO-2002026837-A2 SUPPORTED TITANIUM CATALYST SYSTEM BOREALIS TECHNOLOGY OY (FI) 2002-04-04 WO claimed
WO-2002018046-A1 SUPPORTED CATALYST BOREALIS TECHNOLOGY OY (FI) 2002-03-07 WO claimed
CN-110709396-A Novel compound inhibitors of the YAP/TAZ-TEAD interaction and their use in the treatment of malignant mesothelioma 伊文蒂瓦公司 2020-01-17 CN disclosed
CN-104470925-A Imidazotriazinecarbonitriles useful as kinase inhibitors BRISTOL MYERS SQUIBB CO 2015-03-25 CN disclosed
US-7592456-B2 Arylsulfonylnaphthalene derivatives as 5HT2A antagonists MERCK SHARP & DOHME LIMITED (GB) 2009-09-22 US disclosed
EP-1824817-B1 ARYLSULFONYLNAPHTHALENE DERIVATIVES AS 5HT2A ANTAGONISTS MERCK SHARP & DOHME (GB) 2009-02-04 EP disclosed
US-20070281952-A1 Arylsulfonylnaphthalene Derivatives As 5Ht2a Antagonists MERCK SHARPE & DOHME LIMITED (GB) 2007-12-06 US disclosed
US-20040014912-A1 Supported titanium catalyst system BOREALIS TECHNOLOGY OY (FI) 2004-01-22 US disclosed
US-20030166460-A1 Supported catalyst BOREALIS TECHNOLOGY OY (FI) 2003-09-04 US disclosed
EP-1322676-A2 SUPPORTED TITANIUM CATALYST SYSTEM Borealis Technology Oy (FI) 2003-07-02 EP disclosed
EP-1313561-A1 SUPPORTED CATALYST Borealis Technology Oy (FI) 2003-05-28 EP disclosed
WO-2002026837-A2 SUPPORTED TITANIUM CATALYST SYSTEM BOREALIS TECHNOLOGY OY (FI) 2002-04-04 WO disclosed
WO-2002018046-A1 SUPPORTED CATALYST BOREALIS TECHNOLOGY OY (FI) 2002-03-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070281952-A1 Arylsulfonylnaphthalene Derivatives As 5Ht2a Antagonists HTR2A, HTR2C, HTR1A LMNA 1186/4885KDM4E 4020/4885L3MBTL1 2951/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.