Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14764013 | 0.82 | TRPA1 (0.32) | — | |
| SCHEMBL158756 | 0.81 | LMNA (0.36) | — | |
| SCHEMBL3585938 | 0.79 | ALDH1A1 (0.40) | — | |
| SCHEMBL1145324 | 0.78 | CSNK1E (0.41) | — | |
| SCHEMBL7030565 | 0.78 | ALOX5 (0.33) | — | |
| SCHEMBL4070717 | 0.78 | LMNA (0.31) | — | |
| SCHEMBL3589049 | 0.77 | CSNK1E (0.43) | — | |
| SCHEMBL3582718 | 0.77 | CSNK1E (0.43) | — | |
| SCHEMBL3584428 | 0.77 | CSNK1E (0.43) | — | |
| SCHEMBL3587334 | 0.77 | CSNK1E (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103664637-A | Alkynyl phenyl derivative compounds for treating ophthalmic diseases and disorders | ACUCELA INC | 2014-03-26 | — | — | CN | claimed |
| CN-101784188-B | Alkynyl phenyl derivative compounds for the treatment of ophthalmic diseases and disorders | ACUCELA INC | 2014-02-12 | — | — | CN | claimed |
| CN-101784188-A | Alkynyl phenyl derivative compounds for the treatment of ophthalmic diseases and disorders | ACUCELA INC | 2010-07-21 | — | — | CN | claimed |
| US-20220175700-A1 | VISUAL CYCLE MODULATORS | UNIV CASE WESTERN RESERVE (US) | 2022-06-09 | — | — | US | disclosed |
| US-11253489-B2 | Visual cycle modulators | CASE WESTERN RESERVE UNIVERSITY (US) | 2022-02-22 | — | — | US | disclosed |
| US-20200060996-A1 | VISUAL CYCLE MODULATORS | THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERAN AFFAIRS | 2020-02-27 | — | — | US | disclosed |
| CN-105541769-A | Alkynyl phenyl derivative compounds for treating ophthalmic diseases and disorders | ACUCELA INC | 2016-05-04 | — | — | CN | disclosed |
| CN-103664637-B | Be used for the treatment of ophthalmic diseases and disorderly alkynyl phenyl derivative compounds | ACUCELA INC. (US) | 2016-02-03 | — | — | CN | disclosed |
| CN-103664637-A | Alkynyl phenyl derivative compounds for treating ophthalmic diseases and disorders | ACUCELA INC | 2014-03-26 | — | — | CN | disclosed |
| CN-101784188-B | Alkynyl phenyl derivative compounds for the treatment of ophthalmic diseases and disorders | ACUCELA INC | 2014-02-12 | — | — | CN | disclosed |
| CN-101784188-A | Alkynyl phenyl derivative compounds for the treatment of ophthalmic diseases and disorders | ACUCELA INC | 2010-07-21 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220175700-A1 | VISUAL CYCLE MODULATORS | ALDH1A2, UACA, NR2E3 | HRH1 1786/4885HTR2A 1598/4885 |
| US-20200060996-A1 | VISUAL CYCLE MODULATORS | ALDH1A2, UACA, NR2E3 | HRH1 1786/4885HTR2A 1598/4885 |
| US-11253489-B2 | Visual cycle modulators | ALDH1A2, UACA, NR2E3 | HRH1 1786/4885HTR2A 1598/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.