Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CCR6 | P51684 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8008688 | 0.72 | SMN1; SMN2 (0.55) | SMN1; SMN2ALDH1A1HTTKMT2AL3MBTL1 | |
| SCHEMBL1320968 | 0.71 | GRIK1 (0.49) | SMN1; SMN2HCAR1ALDH1A1HTTKMT2A | |
| SCHEMBL29444848 | 0.71 | GRIK1 (0.49) | SMN1; SMN2HCAR1ALDH1A1HTTKMT2A | |
| SCHEMBL5378943 | 0.70 | KMT2A (0.46) | SMN1; SMN2HCAR1ALDH1A1HTTKMT2A | |
| SCHEMBL4560490 | 0.70 | HCAR1 (0.43) | SMN1; SMN2HCAR1ALDH1A1HTTKMT2A | |
| SCHEMBL11862671 | 0.68 | HCAR1 (0.47) | HCAR1ALDH1A1HTTKMT2ATSHR | |
| SCHEMBL710745 | 0.68 | TLR9 (0.59) | ALDH1A1HTTKMT2AHSD17B10LMNA | |
| SCHEMBL29510755 | 0.68 | TLR9 (0.59) | ALDH1A1HTTKMT2AHSD17B10LMNA | |
| SCHEMBL1274938 | 0.67 | HTT (0.73) | SMN1; SMN2ALDH1A1HTTKMT2ALMNA | |
| SCHEMBL22493009 | 0.67 | ALDH1A1 (0.56) | SMN1; SMN2HCAR1ALDH1A1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2038263-B1 | NOVEL AROMATIC AZA HETEROCYCLES, METHOD OF PRODUCTION AND USE OF THE MATERIAL IN ORGANIC ELECTRONICS | OSRAM OPTO SEMICONDUCTORS GMBH (DE) | 2014-03-05 | — | — | EP | disclosed |
| US-8232393-B2 | Aromatic AZA heterocycles, method of production and use of the material in organic electronics | OSRAM OPTO SEMICONDUCTORS GMBH (DE) | 2012-07-31 | — | — | US | disclosed |
| US-20090318691-A1 | Novel Aromatic AZA Heterocycles, Method of Production and Use of the Material in Organic Electronics | OSRAM OPTO SEMICONDUCTORS GMBH (DE) | 2009-12-24 | — | — | US | disclosed |
| EP-2038263-A1 | NOVEL AROMATIC AZA HETEROCYCLES, METHOD OF PRODUCTION AND USE OF THE MATERIAL IN ORGANIC ELECTRONICS | OSRAM Opto Semiconductors GmbH (DE) | 2009-03-25 | — | — | EP | disclosed |
| WO-2008006738-A1 | NOVEL AROMATIC AZA HETEROCYCLES, METHOD OF PRODUCTION AND USE OF THE MATERIAL IN ORGANIC ELECTRONICS | OSRAM OPTO SEMICONDUCTORS GMBH (DE) | 2008-01-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090318691-A1 | Novel Aromatic AZA Heterocycles, Method of Production and Use of the Material in Organic Electronics | SLC25A21, AOC2, SLC19A1 | SMN1; SMN2 2896/4885HCAR1 3533/4885ALDH1A1 728/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.