SCHEMBL407183

SCHEMBL407183

N#Cc1cnc(N)n1C#N

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CSNK1A1 P48729 1/20 0.31
CLK4 Q9HAZ1 1/20 0.31
HTT P42858 1/20 0.31
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
GAA P10253 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18833440 0.69 AR (0.30)
SCHEMBL29071257 0.59 ABL1 (0.38) HTTKDM4EALDH1A1LMNA
SCHEMBL22939902 0.59 TGFBR1 (0.46)
SCHEMBL254689 0.59
SCHEMBL19437227 0.56
Iodide SCHEMBL27373060 0.56 HDAC8 (0.32) KDM4EALDH1A1L3MBTL1
SCHEMBL11299278 0.55
SCHEMBL766574 0.55
SCHEMBL312324 0.54
SCHEMBL305290 0.51

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102405261-B Colored curable composition, color resist, ink-jet ink, color filter and method for producing the same, solid-state image pickup device, image display device, liquid crystal display, organic EL display, and colorant compound and tautomer thereof FUJIFILM CORP. (JP) 2014-10-15 CN disclosed
US-8741508-B2 Colored curable composition, color resist, ink-jet ink, color filter and method for producing the same, solid-state image pickup device, image display device, liquid crystal display, organic el display, and colorant compound and tautomer thereof FUJIFILM CORPORATION (JP) 2014-06-03 US disclosed
EP-2440618-A1 COLORED CURABLE COMPOSITION, COLOR RESIST, INK-JET INK, COLOR FILTER AND METHOD FOR PRODUCING THE SAME, SOLID-STATE IMAGE PICKUP DEVICE, IMAGE DISPLAY DEVICE, LIQUID CRYSTAL DISPLAY, ORGANIC EL DISPLAY, AND COLORANT COMPOUND AND TAUTOMER THEREOF FUJIFILM Corporation (JP) 2012-04-18 EP disclosed
US-8158317-B2 Color reproducibility, image storability FUJIFILM CORPORATION (JP) 2012-04-17 US disclosed
US-20120021354-A1 COLORED CURABLE COMPOSITION, COLOR RESIST, INK-JET INK, COLOR FILTER AND METHOD FOR PRODUCING THE SAME, SOLID-STATE IMAGE PICKUP DEVICE, IMAGE DISPLAY DEVICE, LIQUID CRYSTAL DISPLAY, ORGANIC EL DISPLAY, AND COLORANT COMPOUND AND TAUTOMER THEREOF FUJIFILM CORPORATION (JP) 2012-01-26 US disclosed
US-20110144107-A1 COMPOUNDS AND COMPOSITIONS USEFUL FOR THE TREATMENT OF MALARIA IRM LLC (BM) 2011-06-16 US disclosed
CN-102089278-A Compounds and compositions useful for the treatment of malaria IRM LLC 2011-06-08 CN disclosed
WO-2010143745-A1 COLORED CURABLE COMPOSITION, COLOR RESIST, INK-JET INK, COLOR FILTER AND METHOD FOR PRODUCING THE SAME, SOLID-STATE IMAGE PICKUP DEVICE, IMAGE DISPLAY DEVICE, LIQUID CRYSTAL DISPLAY, ORGANIC EL DISPLAY, AND COLORANT COMPOUND AND TAUTOMER THEREOF FUJIFILM CORPORATION (JP) 2010-12-16 WO disclosed
US-20080081269-A1 AZO DYE COMPOUND, COLORING COMPOSITION, INK SHEET FOR THERMAL TRANSFER RECORDING, THERMAL TRANSFER RECORDING METHOD, COLOR TONER, INK FOR INKJET, AND COLOR FILTER FUJIFILM CORPORATION (JP) 2008-04-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110144107-A1 COMPOUNDS AND COMPOSITIONS USEFUL FOR THE TREATMENT OF MALARIA G6PD, DHFR, SGMS1 CSNK1A1 3799/4885CLK4 4740/4885HTT 3656/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.