SCHEMBL4176758

SCHEMBL4176758

NNC(=O)c1ccc(Oc2ccc(C(=O)NN)cc2)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.70
CA2 P00918 2/20 0.70
HPGD P15428 3/20 0.63
HTT P42858 2/20 0.63
TSHR P16473 1/20 0.63
SMN1; SMN2 Q16637 1/20 0.63
MPO P05164 2/20 0.61
CYP3A4 P08684 2/20 0.61
KDM5A P29375 1/20 0.61
BLM P54132 1/20 0.61
GFER P55789 1/20 0.61
PMP22 Q01453 1/20 0.61
HIF1A Q16665 1/20 0.61
MAPT P10636 6/20 0.61
ALDH1A1 P00352 5/20 0.59
KDM4E B2RXH2 2/20 0.59
OGG1 O15527 1/20 0.59
LMNA P02545 1/20 0.59
L3MBTL1 Q9Y468 1/20 0.59
KMT2A Q03164 2/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11132687 0.92 PARP10 (0.63) CA1CA2HPGDHTTTSHR
SCHEMBL2835202 0.92 ALDH1A1 (0.65) CA1CA2HPGDHTTTSHR
SCHEMBL16827365 0.90 CA1 (0.59) CA1CA2HPGDHTTTSHR
SCHEMBL2678949 0.85 MPO (0.80) CA1CA2HTTMPOCYP3A4
SCHEMBL343630 0.85 MPO (0.80) CA1CA2HTTMPOCYP3A4
SCHEMBL28188923 0.83 MPO (0.76) CA1CA2HTTMPOCYP3A4
SCHEMBL407188 0.83 CA1 (1.00) CA1CA2HTTSMN1; SMN2CYP3A4
SCHEMBL16193119 0.83 CA1 (0.66) CA1CA2HTTSMN1; SMN2MPO
SCHEMBL18068446 0.83 CA1 (0.66) CA1CA2HTTMPOCYP3A4
SCHEMBL3533538 0.82 RAB9A (0.62) CA1CA2HPGDHTTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4381886-A HYDRAZIDE-IMIDE COPOLYMER HITACHI, LTD. (JP) 1983-05-03 US claimed
JP-57014630-A None JP disclosed
EP-3125033-B1 LIQUID CRYSTAL DISPLAY DEVICE JNC CORP (JP) 2021-06-02 EP disclosed
US-10968392-B2 Liquid crystal aligning agent for photoalignment, liquid crystal alignment film and liquid crystal display device using it, and diamine and polymer JNC CORPORATION (JP) 2021-04-06 US disclosed
US-10782566-B2 Liquid crystal display device JNC CORPORATION (JP) 2020-09-22 US disclosed
EP-3179303-B1 LIQUID CRYSTAL DISPLAY ELEMENT JNC CORP (JP) 2020-04-01 EP disclosed
US-10435627-B2 Liquid crystal display device JNC CORPORATION (JP) 2019-10-08 US disclosed
EP-3133136-B1 LIQUID CRYSTAL DISPLAY DEVICE JNC CORP (JP) 2019-08-07 EP disclosed
EP-3163368-B1 LIQUID CRYSTAL DISPLAY ELEMENT JNC CORP (JP) 2019-06-26 EP disclosed
US-20190127643-A1 LIQUID CRYSTAL ALIGNING AGENT FOR PHOTOALIGNMENT, LIQUID CRYSTAL ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY DEVICE USING IT, AND DIAMINE AND POLYMER JNC CORPORATION (JP) 2019-05-02 US disclosed
EP-3125033-A1 LIQUID CRYSTAL DISPLAY ELEMENT JNC Corporation (JP) 2017-02-01 EP disclosed
US-20160369168-A1 LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2016-12-22 US disclosed
US-20150275089-A1 LIQUID CRYSTAL DISPLAY ELEMENT AND METHOD FOR MANUFACTURING SAME JNC PETROCHEMICAL CORPORATION (JP) 2015-10-01 US disclosed
US-20090140510-A1 Porous igniter coating for use in automotive airbag inflators MENDENHALL IVAN V 2009-06-04 US disclosed
US-20050115650-A1 Foamed igniter for use in automotive airbag inflators AUTOLIV ASP, INC. 2005-06-02 US disclosed
US-20040108030-A1 Porous igniter coating for use in automotive airbag inflators AUTOLIV ASP, INC. 2004-06-10 US disclosed
US-4800214-A Open cell body made of hard vinyl chloride resin LONSEAL CORPORATION (JP) 1989-01-24 US disclosed
US-4797426-A HIGH MOLECULAR WEIGHT ACRYLIC RESIN, METAL STABILIZER LONSEAL CORPORATION (JP) 1989-01-10 US disclosed
US-4381886-A HYDRAZIDE-IMIDE COPOLYMER HITACHI, LTD. (JP) 1983-05-03 US disclosed
JP-S5714630-A PREPARATION OF OPEN-CELL FOAM LONSEAL CORP 1982-01-25 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10968392-B2 Liquid crystal aligning agent for photoalignment, liquid crystal alignment film and liquid crystal display device using it, and diamine and polymer DDT, DCLRE1A, DVL1 CA1 992/4885CA2 2569/4885HPGD 4188/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.