Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.59 |
| ▸ | LPAR3 | Q9UBY5 | 8/20 | 0.50 |
| ▸ | LPAR2 | Q9HBW0 | 6/20 | 0.50 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL345903 | 0.98 | TSHR (0.62) | TSHRLPAR3LPAR2LPAR1THRB | |
| Ammonia Solution, Strong SCHEMBL18138996 | 0.98 | TSHR (0.58) | TSHRLPAR3LPAR2LPAR1THRB | |
| SCHEMBL346866 | 0.98 | TSHR (0.62) | TSHRLPAR3LPAR2LPAR1THRB | |
| SCHEMBL15166 | 0.98 | TSHR (0.62) | TSHRLPAR3LPAR2LPAR1THRB | |
| SCHEMBL345787 | 0.98 | TSHR (0.62) | TSHRLPAR3LPAR2LPAR1THRB | |
| SCHEMBL345385 | 0.98 | TSHR (0.62) | TSHRLPAR3LPAR2LPAR1THRB | |
| SCHEMBL1653308 | 0.98 | TSHR (0.62) | TSHRLPAR3LPAR2LPAR1THRB | |
| SCHEMBL346923 | 0.98 | TSHR (0.62) | TSHRLPAR3LPAR2LPAR1THRB | |
| SCHEMBL15795 | 0.98 | TSHR (0.62) | TSHRLPAR3LPAR2LPAR1THRB | |
| SCHEMBL1651991 | 0.98 | TSHR (0.62) | TSHRLPAR3LPAR2LPAR1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 489 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11992538-B2 | Polymerizable dental composition based on condensed silanes | VOCO GMBH (DE) | 2024-05-28 | — | — | US | claimed |
| US-20240018362-A1 | Acrylate Structural Adhesive Free of MMA | SCIGRIP ADHESIVES LTD. (GB) | 2024-01-18 | — | — | US | claimed |
| EP-4247909-A1 | ACRYLATE STRUCTURAL ADHESIVE FREE OF MMA | Zephyros Inc. (US) | 2023-09-27 | — | — | EP | claimed |
| WO-2023175033-A1 | AUTONOMOUSLY CURABLE AND FOAMABLE TWO-COMPONENT ACRYLIC ADHESIVE | ZEPHYROS, INC. (US) | 2023-09-21 | — | — | WO | claimed |
| EP-2450027-B1 | DENTAL COMPOSITIONS HAVING SPECIAL FUNCTIONALITY AND TRI-BARREL PACKAGING | KERR CORP (US) | 2023-01-11 | — | — | EP | claimed |
| WO-2022106722-A1 | ACRYLATE STRUCTURAL ADHESIVE FREE OF MMA | ZEPHYROS, INC. (US) | 2022-05-27 | — | — | WO | claimed |
| US-20210052469-A1 | POLYMERIZABLE DENTAL COMPOSITION BASED ON CONDENSED SILANES | VOCO GMBH (DE) | 2021-02-25 | — | — | US | claimed |
| EP-3782599-A1 | DENTAL POLYMERIZABLE COMPOSITION BASED ON CONDENSED SILANES | VOCO GmbH (DE) | 2021-02-24 | — | — | EP | claimed |
| CN-108250900-B | Water-based epoxy graphene low-zinc antirust primer | 明光科迪新材料有限公司 | 2020-09-04 | — | — | CN | claimed |
| CN-108165069-B | High-content aqueous graphene dispersion liquid and preparation method thereof | 明光科迪新材料有限公司 | 2020-09-01 | — | — | CN | claimed |
| EP-1498098-B1 | Adhesive composition with decreased polarity upon polymerization | 3M ESPE AG (DE) | 2006-05-03 | — | — | EP | claimed |
| US-6984673-B2 | Dental cement composition | KURARAY CO., LTD. (JP) | 2006-01-10 | — | — | US | claimed |
| WO-2005004819-A1 | ADHESIVE COMPOSITION WITH DECREASED POLARITY UPON POLYMERIZATION | 3M ESPE AG (DE) | 2005-01-20 | — | — | WO | claimed |
| EP-1498098-A1 | Adhesive composition with decreased polarity upon polymerization | 3M ESPE AG (DE) | 2005-01-19 | — | — | EP | claimed |
| US-20040176496-A1 | Light-curing dental adhesive compositions | DENTKIST, INC. (KR) | 2004-09-09 | — | — | US | claimed |
| EP-0509516-B1 | Dental restoration composition | SANKIN IND CO (JP) | 1997-03-26 | — | — | EP | claimed |
| EP-0509516-A2 | Dental restoration composition | SANKIN KOGYO KABUSHIKI KAISHA (JP) | 1992-10-21 | — | — | EP | claimed |
| EP-0012949-B1 | COATING COMPOSITIONS, PROCESS FOR PRODUCING A CROSS-LINKED COATING FILM WITH SUCH COMPOSITIONS AND THUS PRODUCED ARTICLES | MITSUBISHI RAYON CO., LTD. (JP) | 1982-12-01 | — | — | EP | claimed |
| US-4274933-A | FORMING A CROSSLINKED HARDENED FILM ON A SUBSTRATE | MITSUBISHI RAYON CO., LTD. (JP) | 1981-06-23 | — | — | US | claimed |
| EP-0012949-A1 | Coating compositions, process for producing a cross-linked coating film with such compositions and thus produced articles | MITSUBISHI RAYON CO., LTD. (JP) | 1980-07-09 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11992538-B2 | Polymerizable dental composition based on condensed silanes | NCAPH, RCC1, NCAPD2 | TSHR 4596/4885LPAR3 1042/4885LPAR2 2192/4885 |
| US-20040176496-A1 | Light-curing dental adhesive compositions | HBG2, GRIN2A, HBG1 | TSHR 4149/4885LPAR3 1340/4885LPAR2 1765/4885 |
| US-20210052469-A1 | POLYMERIZABLE DENTAL COMPOSITION BASED ON CONDENSED SILANES | NCAPH, RCC1, NCAPD2 | TSHR 4596/4885LPAR3 1042/4885LPAR2 2192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.