SCHEMBL4072179

SCHEMBL4072179

O=C(O)c1cc(C(F)F)nn1-c1ncccc1Cl

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.44
GAA P10253 1/20 0.44
LIMK1 P53667 2/20 0.39
LIMK2 P53671 2/20 0.39
MALT1 Q9UDY8 3/20 0.36
SMARCA2 P51531 1/20 0.35
KDM4E B2RXH2 1/20 0.35
MAPT P10636 1/20 0.35
LMNA P02545 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
TRPA1 O75762 3/20 0.34
PTGS2 P35354 1/20 0.34
TRPV1 Q8NER1 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30070407 1.00 ALDH1A1 (0.44) ALDH1A1GAALIMK1LIMK2MALT1
SCHEMBL14698292 0.90 LIMK1 (0.39) LIMK1LIMK2MALT1SMARCA2TRPA1
SCHEMBL15775839 0.89 SCN9A (0.39) LIMK1LIMK2MALT1SMARCA2SMN1; SMN2
SCHEMBL951259 0.88 ALDH1A1 (0.58) ALDH1A1GAAMALT1LMNASMN1; SMN2
SCHEMBL25275622 0.83 ALDH1A1 (0.44) ALDH1A1LIMK1LIMK2KDM4EMAPT
SCHEMBL30466605 0.83 ALDH1A1 (0.44) ALDH1A1LIMK1LIMK2KDM4EMAPT
SCHEMBL29558300 0.82 MALT1 (0.40) ALDH1A1GAAMALT1LMNASMN1; SMN2
SCHEMBL384656 0.82 KMT2A (0.43) MALT1KDM4ELMNASMN1; SMN2
SCHEMBL958268 0.82 MALT1 (0.40) ALDH1A1GAAMALT1LMNASMN1; SMN2
SCHEMBL16014740 0.81 NPC1 (0.37) ALDH1A1GAAMALT1MAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4376616-A1 METHOD FOR CONTROLLING DIAMIDE RESISTANT PESTS & COMPOUNDS THEREFOR Syngenta Crop Protection AG (CH) 2024-06-05 EP disclosed
CN-118076228-A Methods for controlling diamide-resistant pests and compounds thereof 先正达农作物保护股份公司 2024-05-24 CN disclosed
CN-117813006-A Methods for controlling diamide-resistant pests and compounds thereof 先正达农作物保护股份公司 2024-04-02 CN disclosed
CN-117715523-A Methods for controlling diamide-resistant pests and compounds thereof 先正达农作物保护股份公司 2024-03-15 CN disclosed
WO-2023110710-A1 METHOD FOR CONTROLLING DIAMIDE RESISTANT PESTS & COMPOUNDS THEREFOR SYNGENTA CROP PROTECTION AG (CH) 2023-06-22 WO disclosed
WO-2023110710-A1 METHOD FOR CONTROLLING DIAMIDE RESISTANT PESTS & COMPOUNDS THEREFOR SYNGENTA CROP PROTECTION AG (CH) 2023-06-22 WO disclosed
WO-2023006634-A1 METHOD FOR CONTROLLING DIAMIDE RESISTANT PESTS & COMPOUNDS THEREFOR SYNGENTA CROP PROTECTION AG (CH) 2023-02-02 WO disclosed
US-9609868-B2 Alkoximino-substituted anthranilic acid diamides as pesticides BAYER CROPSCIENCE AG (DE) 2017-04-04 US disclosed
US-20160007603-A1 ALKOXIMINO-SUBSTITUTED ANTHRANILIC ACID DIAMIDES AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2016-01-14 US disclosed
EP-2964629-A1 ALKOXIMINO-SUBSTITUTED ANTHRANILIC ACID DIAMIDES AS PESTICIDES Bayer CropScience Aktiengesellschaft (DE) 2016-01-13 EP disclosed
WO-2014135588-A1 ALKOXIMINO-SUBSTITUTED ANTHRANILIC ACID DIAMIDES AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2014-09-12 WO disclosed
WO-2014128136-A1 ANTHRANILAMIDE COMPOUNDS AND THEIR USE AS PESTICIDES BASF SE (DE) 2014-08-28 WO disclosed
US-8658801-B2 Pesticides containing a bicyclic bisamide structure SYNGENTA CROP PROTECTION, LLC (US) 2014-02-25 US disclosed
US-20090298816-A1 PESTICIDES CONTAINING A BICYCLIC BISAMIDE STRUCTURE SYNGENTA CROP PROTECTION, INC. (US) 2009-12-03 US disclosed
EP-1984354-B1 PESTICIDES CONTAINING A BICYCLIC BISAMIDE STRUCTURE SYNGENTA PARTICIPATIONS AG (CH) 2009-08-05 EP disclosed
CN-101426779-A Pesticide containing bicyclic bisamide structure SYNGENTA PARTICIPATIONS AG (CH) 2009-05-06 CN disclosed
EP-1984354-A1 PESTICIDES CONTAINING A BICYCLIC BISAMIDE STRUCTURE Syngeta Participations AG (CH) 2008-10-29 EP disclosed
WO-2007093402-A1 PESTICIDES CONTAINING A BICYCLIC BISAMIDE STRUCTURE SYNGENTA PARTICIPATIONS AG (CH) 2007-08-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160007603-A1 ALKOXIMINO-SUBSTITUTED ANTHRANILIC ACID DIAMIDES AS PESTICIDES ANTXR2, DDT, DAO ALDH1A1 670/4885GAA 718/4885LIMK1 4769/4885
US-20090298816-A1 PESTICIDES CONTAINING A BICYCLIC BISAMIDE STRUCTURE DDT, ACHE, GAP43 ALDH1A1 729/4885GAA 2536/4885LIMK1 2859/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.