Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | G6PC1 | P35575 | 1/20 | 0.56 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | FOS | P01100 | 1/20 | 0.46 |
| ▸ | JUN | P05412 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4079893 | 0.90 | G6PC1 (0.45) | G6PC1CHRM5ALDH1A1KMT2AFOS | |
| SCHEMBL4074955 | 0.79 | MEN1 (0.41) | G6PC1ALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL4789340 | 0.76 | MTNR1A (0.47) | — | |
| SCHEMBL23346763 | 0.75 | CHRM5 (0.49) | G6PC1CHRM5TAAR1ALDH1A1KMT2A | |
| SCHEMBL1577336 | 0.73 | CRHBP (0.38) | ALDH1A1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL20080897 | 0.73 | CHRM5 (0.60) | G6PC1CHRM5TAAR1NPC1RAB9A | |
| SCHEMBL22814819 | 0.72 | CHRM5 (0.45) | G6PC1CHRM5TAAR1ALDH1A1KMT2A | |
| SCHEMBL4111701 | 0.71 | CYP1A2 (0.68) | CHRM5ALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL4111704 | 0.71 | CYP1A2 (0.68) | CHRM5ALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL2121150 | 0.71 | CHRM5 (0.72) | G6PC1CHRM5TAAR1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009155362-A1 | SMALL MOLECULE HEMATOPOIETIC GROWTH FACTOR MIMETIC COMPOUNDS AND THEIR USES | LIGAND PHARMACEUTICALS INC. (US) | 2009-12-23 | — | — | WO | disclosed |