Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | G6PC1 | P35575 | 2/20 | 0.33 |
| ▸ | FURIN | P09958 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4073070 | 0.79 | G6PC1 (0.56) | MEN1KMT2AMAPTTDP1ALDH1A1 | |
| SCHEMBL4080914 | 0.78 | ALDH1A1 (0.49) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL4079893 | 0.74 | G6PC1 (0.45) | MEN1KMT2AMAPTLMNAPTGS2 | |
| SCHEMBL4078063 | 0.73 | PTGS2 (0.36) | MEN1KMT2AMAPTLMNAPTGS2 | |
| SCHEMBL1577336 | 0.73 | CRHBP (0.38) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL1536837 | 0.70 | TP53 (0.44) | KMT2AMAPTPTGS2TP53TDP1 | |
| SCHEMBL1576962 | 0.70 | CRHBP (0.38) | MEN1KMT2ALMNATDP1ALDH1A1 | |
| SCHEMBL4071590 | 0.70 | HDAC8 (0.52) | MEN1KMT2AMAPTLMNATDP1 | |
| SCHEMBL8241465 | 0.68 | ALDH1A1 (0.48) | KMT2AMAPTPTGS2TP53TDP1 | |
| Urea SCHEMBL29001189 | 0.67 | TDP1 (0.52) | MEN1KMT2APTGS2TP53TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009155362-A1 | SMALL MOLECULE HEMATOPOIETIC GROWTH FACTOR MIMETIC COMPOUNDS AND THEIR USES | LIGAND PHARMACEUTICALS INC. (US) | 2009-12-23 | — | — | WO | disclosed |