Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AADAT | Q8N5Z0 | 4/20 | 0.48 |
| ▸ | KYAT1 | Q16773 | 2/20 | 0.48 |
| ▸ | KYAT3 | Q6YP21 | 2/20 | 0.48 |
| ▸ | GOT1 | P17174 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 3/20 | 0.40 |
| ▸ | PYGL | P06737 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | F7 | P08709 | 1/20 | 0.40 |
| ▸ | F3 | P13726 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4073194 | 0.89 | KDM4E (0.62) | AADATKYAT1KYAT3GOT1KDM4E | |
| SCHEMBL4064369 | 0.84 | AADAT (0.54) | AADATKYAT1KYAT3GOT1POLB | |
| SCHEMBL4064371 | 0.84 | AADAT (0.54) | AADATKYAT1KYAT3GOT1POLB | |
| SCHEMBL4065939 | 0.84 | AADAT (0.54) | AADATKYAT1KYAT3GOT1POLB | |
| SCHEMBL4067888 | 0.83 | PYGL (0.54) | AADATKYAT1KYAT3GOT1KDM4E | |
| Hydrochloric Acid SCHEMBL4802376 | 0.83 | AADAT (0.52) | AADATKYAT1KYAT3GOT1POLB | |
| Hydrochloric Acid SCHEMBL4802360 | 0.83 | AADAT (0.52) | AADATKYAT1KYAT3GOT1POLB | |
| SCHEMBL4066129 | 0.82 | AADAT (0.46) | AADATKYAT1KYAT3GOT1KDM4E | |
| SCHEMBL27542522 | 0.79 | AADAT (0.55) | AADATKYAT1KYAT3GOT1 | |
| SCHEMBL4891481 | 0.79 | AADAT (0.59) | AADATKYAT1KYAT3GOT1PYGL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1819332-B1 | PYRROLOPYRIDINE-2-CARBOXYLIC ACID AMIDES | PROSIDION LTD (GB) | 2009-03-11 | — | — | EP | disclosed |