Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AADAT | Q8N5Z0 | 4/20 | 0.54 |
| ▸ | KYAT1 | Q16773 | 2/20 | 0.54 |
| ▸ | KYAT3 | Q6YP21 | 2/20 | 0.54 |
| ▸ | GOT1 | P17174 | 1/20 | 0.54 |
| ▸ | PYGL | P06737 | 1/20 | 0.52 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4064369 | 1.00 | AADAT (0.54) | AADATKYAT1KYAT3GOT1PYGL | |
| SCHEMBL4065939 | 1.00 | AADAT (0.54) | AADATKYAT1KYAT3GOT1PYGL | |
| Hydrochloric Acid SCHEMBL4802360 | 0.99 | AADAT (0.52) | AADATKYAT1KYAT3GOT1PYGL | |
| Hydrochloric Acid SCHEMBL4802376 | 0.99 | AADAT (0.52) | AADATKYAT1KYAT3GOT1PYGL | |
| SCHEMBL2222575 | 0.87 | OPRL1 (0.50) | OPRL1 | |
| SCHEMBL9690349 | 0.87 | CCKBR (0.52) | AADATKYAT1KYAT3GOT1 | |
| SCHEMBL7356369 | 0.87 | OPRL1 (0.50) | OPRL1 | |
| SCHEMBL4073290 | 0.84 | AADAT (0.48) | AADATKYAT1KYAT3GOT1PYGL | |
| SCHEMBL4891481 | 0.83 | AADAT (0.59) | AADATKYAT1KYAT3GOT1PYGL | |
| SCHEMBL5629021 | 0.83 | AADAT (0.55) | AADATKYAT1KYAT3GOT1PYGL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090099176-A1 | PYRROLOPYRIDINE-2-CARBOXYLIC ACID AMIDES | PROSIDION LIMITED (GB) | 2009-04-16 | — | — | US | disclosed |
| US-20090099176-A1 | PYRROLOPYRIDINE-2-CARBOXYLIC ACID AMIDES | PROSIDION LIMITED (GB) | 2009-04-16 | — | — | US | disclosed |
| US-20090099176-A1 | PYRROLOPYRIDINE-2-CARBOXYLIC ACID AMIDES | PROSIDION LIMITED (GB) | 2009-04-16 | — | — | US | disclosed |
| EP-1819332-B1 | PYRROLOPYRIDINE-2-CARBOXYLIC ACID AMIDES | PROSIDION LTD (GB) | 2009-03-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090099176-A1 | PYRROLOPYRIDINE-2-CARBOXYLIC ACID AMIDES | PC, GOT2, PDK1 | AADAT 426/4885KYAT1 542/4885KYAT3 1050/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.