Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.46 |
| ▸ | GOT1 | P17174 | 1/20 | 0.46 |
| ▸ | KYAT1 | Q16773 | 1/20 | 0.46 |
| ▸ | KYAT3 | Q6YP21 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | PYGL | P06737 | 1/20 | 0.43 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4066125 | 0.87 | LMNA (0.42) | LMNAALDH1A1KDM4EGAAPYGL | |
| SCHEMBL4067888 | 0.86 | PYGL (0.54) | AADATGOT1KYAT1KYAT3ALDH1A1 | |
| SCHEMBL4073194 | 0.84 | KDM4E (0.62) | AADATGOT1KYAT1KYAT3ALDH1A1 | |
| SCHEMBL13749492 | 0.83 | LMNA (0.41) | LMNAALDH1A1KDM4EGAAPYGL | |
| SCHEMBL4073290 | 0.82 | AADAT (0.48) | AADATGOT1KYAT1KYAT3ALDH1A1 | |
| SCHEMBL4064792 | 0.80 | AADAT (0.54) | AADATGOT1KYAT1KYAT3PYGL | |
| SCHEMBL5629416 | 0.80 | CACNA1S (0.57) | AADATGOT1KYAT1KYAT3LMNA | |
| SCHEMBL4065939 | 0.77 | AADAT (0.54) | AADATGOT1KYAT1KYAT3LMNA | |
| SCHEMBL4064371 | 0.77 | AADAT (0.54) | AADATGOT1KYAT1KYAT3LMNA | |
| SCHEMBL4064369 | 0.77 | AADAT (0.54) | AADATGOT1KYAT1KYAT3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1819332-B1 | PYRROLOPYRIDINE-2-CARBOXYLIC ACID AMIDES | PROSIDION LTD (GB) | 2009-03-11 | — | — | EP | disclosed |