Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.46 |
| ▸ | GOT1 | P17174 | 1/20 | 0.46 |
| ▸ | KYAT1 | Q16773 | 1/20 | 0.46 |
| ▸ | KYAT3 | Q6YP21 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | PYGL | P06737 | 1/20 | 0.45 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.44 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4073290 | 0.89 | AADAT (0.48) | KDM4EALDH1A1GAANPC1AADAT | |
| SCHEMBL4073186 | 0.87 | KDM4E (0.60) | KDM4EALDH1A1GAAMAPK1KMT2A | |
| SCHEMBL4067888 | 0.86 | PYGL (0.54) | KDM4EALDH1A1GAAMAPK1TSHR | |
| SCHEMBL4066129 | 0.84 | AADAT (0.46) | KDM4EALDH1A1GAAMAPK1TSHR | |
| SCHEMBL4065939 | 0.82 | AADAT (0.54) | KMT2AAADATGOT1KYAT1KYAT3 | |
| SCHEMBL4064369 | 0.82 | AADAT (0.54) | KMT2AAADATGOT1KYAT1KYAT3 | |
| SCHEMBL4064371 | 0.82 | AADAT (0.54) | KMT2AAADATGOT1KYAT1KYAT3 | |
| Hydrochloric Acid SCHEMBL4802376 | 0.81 | AADAT (0.52) | KMT2AAADATGOT1KYAT1KYAT3 | |
| Hydrochloric Acid SCHEMBL4802360 | 0.81 | AADAT (0.52) | KMT2AAADATGOT1KYAT1KYAT3 | |
| SCHEMBL5628897 | 0.80 | AADAT (0.52) | KDM4EALDH1A1GAAAADATGOT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1819332-B1 | PYRROLOPYRIDINE-2-CARBOXYLIC ACID AMIDES | PROSIDION LTD (GB) | 2009-03-11 | — | — | EP | disclosed |