Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | FLT1 | P17948 | 1/20 | 0.36 |
| ▸ | NMT1 | P30419 | 3/20 | 0.36 |
| ▸ | TERT | O14746 | 3/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.33 |
| ▸ | EHMT2 | Q96KQ7 | 5/20 | 0.33 |
| ▸ | EHMT1 | Q9H9B1 | 4/20 | 0.33 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | AXL | P30530 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4073121 | 0.86 | NTSR1 (0.36) | POLBMEN1HTTKMT2ATERT | |
| SCHEMBL4074853 | 0.82 | HRH4 (0.40) | HTTTSHRMAPK1SMN1; SMN2TERT | |
| SCHEMBL4076923 | 0.77 | TERT (0.50) | MEN1HTTKMT2AMAPK1TERT | |
| SCHEMBL4073592 | 0.76 | TERT (0.59) | NMT1TERTEHMT2 | |
| SCHEMBL4073298 | 0.74 | TERT (0.40) | MEN1KMT2ATSHRMAPK1SMN1; SMN2 | |
| SCHEMBL4082012 | 0.73 | ACVR1 (0.37) | MEN1KMT2ATSHRTERT | |
| SCHEMBL4076910 | 0.72 | BRD4 (0.35) | TERT | |
| SCHEMBL4081927 | 0.71 | ABCC1 (0.34) | MEN1HTTKMT2ATSHRSMN1; SMN2 | |
| SCHEMBL4081856 | 0.70 | TERT (0.36) | TERTMAP4K4 | |
| SCHEMBL4081462 | 0.70 | HTR1A (0.35) | MEN1KMT2ATSHRSMN1; SMN2TERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6887873-B2 | Triazine derivatives and their application as antitelomerase agents | AVENTIS PHARMA S.A. (FR) | 2005-05-03 | — | — | US | claimed |
| US-20030087931-A1 | Chemical derivatives and their application as antitelomerease agent | AVENTIS PHARMA S.A. (FR) | 2003-05-08 | — | — | US | claimed |
| US-20090226411-A1 | CHEMICAL DERIVATIVES AND THEIR APPLICATION AS ANTITELOMERASE AGENTS | AVENTIS PHARMA S.A. (FR) | 2009-09-10 | — | — | US | disclosed |
| US-7482352-B2 | Chemical derivatives and their application as antitelomerase agents | AVENTIS PHARMA S.A. (FR) | 2009-01-27 | — | — | US | disclosed |
| US-6887873-B2 | Triazine derivatives and their application as antitelomerase agents | AVENTIS PHARMA S.A. (FR) | 2005-05-03 | — | — | US | disclosed |
| US-20050070571-A1 | Chemical derivatives and their application as antitelomerase agents | AVENTIS PHARMA S.A. (FR) | 2005-03-31 | — | — | US | disclosed |
| US-20030087931-A1 | Chemical derivatives and their application as antitelomerease agent | AVENTIS PHARMA S.A. (FR) | 2003-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030087931-A1 | Chemical derivatives and their application as antitelomerease agent | DNASE1L3, SERPINB1, BRDT | POLB 176/4885MEN1 3983/4885HTT 3524/4885 |
| US-20090226411-A1 | CHEMICAL DERIVATIVES AND THEIR APPLICATION AS ANTITELOMERASE AGENTS | DPYD, NTPCR, NME1 | POLB 300/4885MEN1 4234/4885HTT 4783/4885 |
| US-20050070571-A1 | Chemical derivatives and their application as antitelomerase agents | DPYD, NTPCR, NME1 | POLB 300/4885MEN1 4234/4885HTT 4783/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.