Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | MGAM | O43451 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SI | P14410 | 1/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | S100A4 | P26447 | 2/20 | 0.41 |
| ▸ | PTPRC | P08575 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12288740 | 0.87 | ALDH1A1 (0.59) | ALDH1A1TDP1MGAMGAASI | |
| SCHEMBL27632765 | 0.79 | TDP1 (0.50) | ALDH1A1TDP1MGAMGAASI | |
| SCHEMBL30535903 | 0.74 | ALDH1A1 (0.74) | ALDH1A1TDP1MGAMGAASI | |
| SCHEMBL1287837 | 0.74 | ALDH1A1 (0.74) | ALDH1A1TDP1MGAMGAASI | |
| SCHEMBL29337140 | 0.72 | ALDH1A1 (0.71) | ALDH1A1TDP1MGAMGAASI | |
| SCHEMBL30987815 | 0.72 | ALDH1A1 (0.71) | ALDH1A1TDP1MGAMGAASI | |
| Ammonia Solution, Strong SCHEMBL9060371 | 0.72 | ALDH1A1 (0.71) | ALDH1A1TDP1MGAMGAASI | |
| SCHEMBL331601 | 0.71 | ALDH1A1 (0.53) | ALDH1A1TDP1MGAMGAASI | |
| SCHEMBL11032764 | 0.71 | ALDH1A1 (0.49) | ALDH1A1TDP1MGAMGAASI | |
| SCHEMBL4077290 | 0.71 | ALDH1A1 (0.41) | ALDH1A1TDP1MGAMGAASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1972933-B | Heterocyclic carboxamides having microbiocidal activity | SYNGENTA PARTICIPATIONS AG | 2012-07-18 | — | — | CN | disclosed |
| US-7553798-B2 | Heterocyclic carboxamides with microbiocidal activity | SYNGENTA CROP PROTECTION, INC. (US) | 2009-06-30 | — | — | US | disclosed |
| US-20080132557-A1 | Heterocyclic Carboxamides with Microbiocidal Activity | SYNGENTA CROP PROTECTION, INC. (US) | 2008-06-05 | — | — | US | disclosed |
| CN-1972933-A | Heterocyclic carboxamides having microbiocidal activity | SYNGENTA PARTICIPATIONS AG (CH) | 2007-05-30 | — | — | CN | disclosed |
| EP-1758894-A1 | HETEROCYCLIC CARBOXAMIDES WITH MICROBIOCIDAL ACTIVITY | Syngeta Participations AG (CH) | 2007-03-07 | — | — | EP | disclosed |
| WO-2005123722-A1 | HETEROCYCLIC CARBOXAMIDES WITH MICROBIOCIDAL ACTIVITY | SYNGENTA PARTICIPATIONS AG (CH) | 2005-12-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080132557-A1 | Heterocyclic Carboxamides with Microbiocidal Activity | MPO, FPR1, CD14 | ALDH1A1 547/4885TDP1 2558/4885MGAM 431/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.