Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | MGAM | O43451 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | SI | P14410 | 2/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | S100A4 | P26447 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PTPRC | P08575 | 1/20 | 0.35 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12288740 | 0.78 | ALDH1A1 (0.59) | ALDH1A1TDP1MGAMGAASI | |
| SCHEMBL12365094 | 0.78 | HPGD (0.44) | PTPN1HPGDL3MBTL1 | |
| SCHEMBL4083053 | 0.77 | BACE1 (0.39) | ALDH1A1TDP1GAAHSD17B10MEN1 | |
| SCHEMBL15957593 | 0.75 | L3MBTL1 (0.42) | ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL27632765 | 0.74 | TDP1 (0.50) | ALDH1A1TDP1MGAMGAASI | |
| SCHEMBL4209889 | 0.72 | ALDH1A1 (0.57) | ALDH1A1TDP1MGAMGAASI | |
| SCHEMBL4074282 | 0.71 | ALDH1A1 (0.50) | ALDH1A1TDP1MGAMGAASI | |
| SCHEMBL13597747 | 0.71 | HSD17B10 (0.47) | ALDH1A1TDP1HSD17B10MEN1KMT2A | |
| SCHEMBL30535903 | 0.67 | ALDH1A1 (0.74) | ALDH1A1TDP1MGAMGAASI | |
| SCHEMBL1287837 | 0.67 | ALDH1A1 (0.74) | ALDH1A1TDP1MGAMGAASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7553798-B2 | Heterocyclic carboxamides with microbiocidal activity | SYNGENTA CROP PROTECTION, INC. (US) | 2009-06-30 | — | — | US | disclosed |
| US-20080132557-A1 | Heterocyclic Carboxamides with Microbiocidal Activity | SYNGENTA CROP PROTECTION, INC. (US) | 2008-06-05 | — | — | US | disclosed |
| EP-1758894-A1 | HETEROCYCLIC CARBOXAMIDES WITH MICROBIOCIDAL ACTIVITY | Syngeta Participations AG (CH) | 2007-03-07 | — | — | EP | disclosed |
| WO-2005123722-A1 | HETEROCYCLIC CARBOXAMIDES WITH MICROBIOCIDAL ACTIVITY | SYNGENTA PARTICIPATIONS AG (CH) | 2005-12-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080132557-A1 | Heterocyclic Carboxamides with Microbiocidal Activity | MPO, FPR1, CD14 | ALDH1A1 547/4885TDP1 2558/4885MGAM 431/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.