SCHEMBL4074584

SCHEMBL4074584

CCN1C(=CC=C2CCC(C=CC3=[N+](CC)c4ccc(C)cc4C3(C)C)=C2N(c2ccccc2)c2ccccc2)C(C)(C)c2cc(C(F)(F)F)ccc21

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.42
LMNA P02545 2/20 0.42
MAPT P10636 2/20 0.42
THRB P10828 2/20 0.42
HTT P42858 2/20 0.42
RECQL P46063 2/20 0.42
KMT2A Q03164 2/20 0.42
NPC1 O15118 1/20 0.42
USP2 O75604 1/20 0.42
S1PR2 O95136 1/20 0.42
POLB P06746 1/20 0.42
ALPG P10696 1/20 0.42
PKM P14618 1/20 0.42
XBP1 P17861 1/20 0.42
CRHBP P24387 1/20 0.42
RAB9A P51151 1/20 0.42
BLM P54132 1/20 0.42
CRHR2 Q13324 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15959856 1.00 MEN1 (0.42) MEN1LMNAMAPTTHRBHTT
SCHEMBL13424306 0.96 MEN1 (0.43) MEN1LMNAMAPTTHRBHTT
SCHEMBL92082 0.96 MEN1 (0.43) MEN1LMNAMAPTTHRBHTT
SCHEMBL14039782 0.96 MEN1 (0.43) MEN1LMNAMAPTTHRBHTT
SCHEMBL10123395 0.96 MEN1 (0.43) MEN1LMNAMAPTTHRBHTT
SCHEMBL860213 0.94 MEN1 (0.47) MEN1LMNAMAPTTHRBHTT
SCHEMBL12155043 0.90 MEN1 (0.46) MEN1LMNAMAPTTHRBHTT
SCHEMBL24044665 0.90 MEN1 (0.46) MEN1LMNAMAPTTHRBHTT
SCHEMBL12609404 0.90 MEN1 (0.46) MEN1LMNAMAPTTHRBHTT
SCHEMBL10110730 0.86 MEN1 (0.42) MEN1LMNAMAPTTHRBHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9032876-B2 Lithographic printing plate precursor, lithographic printing plate platemaking method, and polymerizable monomer FUJIFILM CORPORATION (JP) 2015-05-19 US disclosed
US-20120295204-A1 PROCESSING METHOD OF LITHOGRAPHIC PRINTING PLATE PREURSOR FUJIFILM CORPORATION (JP) 2012-11-22 US disclosed
US-20120227605-A1 ALUMINUM ALLOY PLATE FOR LITHOGRAPHIC PRINTING PLATE, LITHOGRAPHIC PRINTING PLATE SUPPORT, PRESENSITIZED PLATE, METHOD OF MANUFACTURING ALUMINUM ALLOY PLATE FOR LITHOGRAPHIC PRINTING PLATE AND METHOD OF MANUFACTURING LITHOGRAPHIC PRINTING PLATE SUPPORT FUJIFILM CORPORATION (JP) 2012-09-13 US disclosed
US-20120103220-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR SONOKAWA KOJI (JP) 2012-05-03 US disclosed
US-20110174179-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR, LITHOGRAPHIC PRINTING PLATE PLATEMAKING METHOD, AND POLYMERIZABLE MONOMER FUJIFILM CORPORATION (JP) 2011-07-21 US disclosed
US-20110091814-A1 PROCESS FOR MAKING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2011-04-21 US disclosed
US-20110054212-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND LITHOGRAPHIC PRINTING PROCESS OOHASHI HIDEKAZU 2011-03-03 US disclosed
US-20110017084-A1 IMMERSION TYPE AUTOMATIC DEVELOPING APPARATUS FOR LITHOGRAPHIC PRINTING PLATE AND AUTOMATIC DEVELOPING METHOD FUJIFILM CORPORATION (JP) 2011-01-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110174179-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR, LITHOGRAPHIC PRINTING PLATE PLATEMAKING METHOD, AND POLYMERIZABLE MONOMER SORT1, ELOVL6, SCD5 MEN1 3045/4885LMNA 58/4885MAPT 2383/4885
US-20110054212-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND LITHOGRAPHIC PRINTING PROCESS FLNA, PFN1, FLNB MEN1 832/4885LMNA 321/4885MAPT 353/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.