SCHEMBL407496

SCHEMBL407496

O=C(O)CC1CCc2ccccc2O1

nearest known ligand 0.63

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.54
HTR1A P08908 4/20 0.51
SIGMAR1 Q99720 2/20 0.51
ADRA2A P08913 1/20 0.51
ADRA2B P18089 1/20 0.51
ADRA2C P18825 1/20 0.51
ITGB3 P05106 2/20 0.49
ITGA2B P08514 2/20 0.49
HTR1D P28221 2/20 0.48
DRD2 P14416 5/20 0.47
DRD4 P21917 5/20 0.47
DRD3 P35462 5/20 0.47
DRD1 P21728 2/20 0.47
DRD5 P21918 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16428909 1.00 CA2 (0.54) CA2HTR1ASIGMAR1ADRA2AADRA2B
SCHEMBL15211143 1.00 CA2 (0.54) CA2HTR1ASIGMAR1ADRA2AADRA2B
SCHEMBL1567100 0.87 CA2 (0.54) CA2HTR1ASIGMAR1ADRA2AADRA2B
SCHEMBL15219505 0.86 CA2 (0.52) CA2HTR1ASIGMAR1ADRA2AADRA2B
SCHEMBL15219843 0.86 CA2 (0.52) CA2HTR1ASIGMAR1ADRA2AADRA2B
SCHEMBL406490 0.86 CA2 (0.56) CA2HTR1ASIGMAR1ADRA2AADRA2B
SCHEMBL15210953 0.84 HTT (0.60) CA2HTR1ASIGMAR1ADRA2AADRA2B
SCHEMBL15210950 0.84 HTT (0.60) CA2HTR1ASIGMAR1ADRA2AADRA2B
SCHEMBL11217487 0.84 HTR1A (0.51) CA2HTR1ASIGMAR1ADRA2AADRA2B
SCHEMBL24113076 0.83 HTT (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250241298-A1 Liquid Sulfonylurea-Containing Herbicidal Compositions BATTELLE UK LIMITED (GB) 2025-07-31 US disclosed
US-12364261-B2 Liquid sulfonylurea- and Li-salt containing herbicidal compositions BATTELLE UK LIMITED (GB) 2025-07-22 US disclosed
US-12268209-B2 Liquid sulfonylurea-containing herbicidal compositions MITSUI AGRISCIENCE INTERNATIONAL S.A./N.V. (BE) 2025-04-08 US disclosed
CN-116250539-B Ternary weeding composition containing fenpyrazamine and application thereof 青岛清原化合物有限公司 2025-03-18 CN disclosed
CN-117941690-A Weeding composition containing tetrafluoro-clomazone and application thereof 江苏清原农冠杂草防治有限公司 2024-04-30 CN disclosed
CN-117941696-A Herbicidal compositions comprising fused ring substituted aromatic compounds and uses thereof 江苏清原农冠杂草防治有限公司 2024-04-30 CN disclosed
CN-117941694-A Herbicidal compositions comprising substituted pyrimidine formyl oximes and use thereof 江苏清原农冠杂草防治有限公司 2024-04-30 CN disclosed
WO-2024073018-A1 BIODEGRADABLE MICROPARTICLES FOR REDUCING THE VOLATILITY OF BIXOLOZONE FMC CORPORATION (US) 2024-04-04 WO disclosed
EP-4138556-B1 LIQUID SULFONYLUREA HERBICIDE COMPOSITION BATTELLE UK LTD (GB) 2023-12-27 EP disclosed
WO-2023202364-A1 HERBICIDAL COMPOSITION COMPRISING PYRIMIDINE FORMYL OXIME DERIVATIVE AND USE THEREOF 青岛清原作物科学有限公司 2023-10-26 WO disclosed
WO-2001092249-A2 CHIRAL AND ACHIRAL SYNTHESIS OF 2-ACYL SUBSTITUTED CHROMANES AND THEIR DERIVATIVES COR THERAPEUTICS, INC. (US) 2001-12-06 WO disclosed
WO-2001087871-A2 METHODS FOR PRODUCING AMINO SUBSTITUTED CHROMANES AND INTERMEDIATES THEREFOR MILLENNIUM PHARMACEUTICALS, INC. (US) 2001-11-22 WO disclosed
US-5925662-A OXIDASE INHIBITORS SYNTHELABO (FR) 1999-07-20 US disclosed
EP-0859776-A1 COMPOUNDS DERIVED FROM OXAZOLIDIN-2-ONE AND PREPARATION AND THERAPEUTICAL USE THEREOF SYNTHELABO (FR) 1998-08-26 EP disclosed
WO-1997017347-A1 COMPOUNDS DERIVED FROM OXAZOLIDIN-2-ONE AND PREPARATION AND THERAPEUTICAL USE THEREOF SYNTHELABO (FR) 1997-05-15 WO disclosed
US-4208333-A Preparation of chroman-2-acetic acids HOFFMANN-LA ROCHE INC. (US) 1980-06-17 US disclosed
US-4208333-A Preparation of chroman-2-acetic acids HOFFMANN-LA ROCHE INC. (US) 1980-06-17 US disclosed
US-4192816-A Mixtures of 3-pentenenitriles and 3-methylene-pentanenitriles HOFFMANN-LA ROCHE INC. (US) 1980-03-11 US disclosed
US-4186138-A Preparation of chroman-2-acetic acids HOFFMANN-LA ROCHE INC. (US) 1980-01-29 US disclosed
US-4186138-A Preparation of chroman-2-acetic acids HOFFMANN-LA ROCHE INC. (US) 1980-01-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12364261-B2 Liquid sulfonylurea- and Li-salt containing herbicidal compositions LCT, CLIC1, CLIC4 CA2 19/4885HTR1A 3473/4885SIGMAR1 316/4885
US-12268209-B2 Liquid sulfonylurea-containing herbicidal compositions CA2, CA3, DPP4 CA2 1/4885HTR1A 4289/4885SIGMAR1 501/4885
US-20250241298-A1 Liquid Sulfonylurea-Containing Herbicidal Compositions CA2, CA3, DPP4 CA2 1/4885HTR1A 4289/4885SIGMAR1 501/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.