Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CDC25A | P30304 | 1/20 | 0.47 |
| ▸ | CDC25B | P30305 | 1/20 | 0.47 |
| ▸ | CDC25C | P30307 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TLR2 | O60603 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.41 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4072975 | 0.90 | ALDH1A1 (0.50) | ALDH1A1HPGDCDC25ACDC25BCDC25C | |
| SCHEMBL4066911 | 0.89 | ALDH1A1 (0.49) | ALDH1A1HPGDCDC25ACDC25BCDC25C | |
| SCHEMBL18840973 | 0.86 | ALDH1A1 (0.48) | ALDH1A1HPGDMAPTLMNAADORA1 | |
| SCHEMBL18840970 | 0.83 | MAPT (0.48) | ALDH1A1MAPTLMNAADORA1KDM4E | |
| SCHEMBL18840958 | 0.83 | ALDH1A1 (0.48) | ALDH1A1HPGDMAPTSMN1; SMN2LMNA | |
| SCHEMBL4067626 | 0.77 | LMNA (0.55) | ALDH1A1HPGDMAPTSMN1; SMN2LMNA | |
| SCHEMBL4063973 | 0.77 | LMNA (0.55) | ALDH1A1HPGDMAPTSMN1; SMN2LMNA | |
| SCHEMBL31065219 | 0.77 | LMNA (0.55) | ALDH1A1HPGDMAPTSMN1; SMN2LMNA | |
| SCHEMBL3868209 | 0.76 | ALDH1A1 (0.52) | ALDH1A1HPGDMAPTSMN1; SMN2LMNA | |
| SCHEMBL4070954 | 0.74 | HPGD (0.60) | ALDH1A1HPGDMAPTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2033955-A1 | Urea derivatives of 1H-pyrazol-4-carboxylic acid with neutrophil chemotaxis inhibiting activity | Universita' Degli Studi Di Genova (IT) | 2009-03-11 | — | — | EP | claimed |
| EP-2033955-A1 | Urea derivatives of 1H-pyrazol-4-carboxylic acid with neutrophil chemotaxis inhibiting activity | Universita' Degli Studi Di Genova (IT) | 2009-03-11 | — | — | EP | disclosed |