Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CDC25B | P30305 | 3/20 | 0.48 |
| ▸ | CDC25A | P30304 | 1/20 | 0.48 |
| ▸ | CDC25C | P30307 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TLR2 | O60603 | 2/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4072975 | 0.92 | ALDH1A1 (0.50) | ALDH1A1HPGDCDC25BCDC25ACDC25C | |
| SCHEMBL4075658 | 0.89 | ALDH1A1 (0.47) | ALDH1A1HPGDCDC25BCDC25ACDC25C | |
| SCHEMBL4067626 | 0.88 | LMNA (0.55) | ALDH1A1HPGDLMNAMAPTSMN1; SMN2 | |
| SCHEMBL4065398 | 0.82 | MAPT (0.49) | ALDH1A1HPGDLMNAMAPTPAX8 | |
| SCHEMBL4062182 | 0.80 | PAX8 (0.54) | ALDH1A1LMNAMAPTSMN1; SMN2PAX8 | |
| SCHEMBL31065219 | 0.80 | LMNA (0.55) | ALDH1A1HPGDLMNAMAPTSMN1; SMN2 | |
| SCHEMBL4063973 | 0.80 | LMNA (0.55) | ALDH1A1HPGDLMNAMAPTSMN1; SMN2 | |
| SCHEMBL4067165 | 0.80 | MAPT (0.53) | ALDH1A1HPGDLMNAMAPTSMN1; SMN2 | |
| SCHEMBL4066908 | 0.79 | CYP3A4 (0.46) | ALDH1A1HPGDLMNAMAPTSMN1; SMN2 | |
| SCHEMBL4066874 | 0.75 | MAPT (0.47) | ALDH1A1LMNAMAPTSMN1; SMN2PAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2033955-A1 | Urea derivatives of 1H-pyrazol-4-carboxylic acid with neutrophil chemotaxis inhibiting activity | Universita' Degli Studi Di Genova (IT) | 2009-03-11 | — | — | EP | disclosed |