Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | CES2 | O00748 | 1/20 | 0.55 |
| ▸ | CES1 | P23141 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | MITF | O75030 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.47 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30475402 | 1.00 | SMN1; SMN2 (0.55) | SMN1; SMN2CES2CES1HTTPRSS1 | |
| SCHEMBL1773780 | 0.84 | CES2 (0.39) | SMN1; SMN2CES2CES1HTTALDH1A1 | |
| SCHEMBL2154161 | 0.84 | HSD17B1 (0.43) | SMN1; SMN2CES2CES1HTTALDH1A1 | |
| SCHEMBL31634804 | 0.84 | CES2 (0.39) | SMN1; SMN2CES2CES1HTTALDH1A1 | |
| SCHEMBL4546533 | 0.82 | HPGD (0.53) | SMN1; SMN2ALDH1A1NPC1LMNAPOLB | |
| SCHEMBL1375362 | 0.82 | HDAC8 (0.41) | SMN1; SMN2CES2CES1HTTALDH1A1 | |
| SCHEMBL2972020 | 0.82 | TAS1R3 (0.51) | SMN1; SMN2CES2CES1HTTALDH1A1 | |
| SCHEMBL4276908 | 0.82 | TRPA1 (0.47) | SMN1; SMN2HTTALDH1A1POLBMAPT | |
| SCHEMBL31590951 | 0.82 | TDP1 (0.48) | SMN1; SMN2HTTALDH1A1POLBMAPT | |
| SCHEMBL14566946 | 0.80 | MAPT (0.70) | SMN1; SMN2CES2CES1HTTPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 227 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104693062-B | Phenylacetylene derivatives and preparation of the side base with ester group, polymerization and methods for using them | 哈尔滨工程大学 | 2017-10-03 | — | — | CN | claimed |
| CN-104910039-A | Functional phenylacetylene compound and preparation method thereof | UNIV HARBIN ENG | 2015-09-16 | — | — | CN | claimed |
| CN-104693062-A | Phenylacetylene derivative with ester group on lateral base band and preparation, polymerization and application methods | UNIV HARBIN ENG | 2015-06-10 | — | — | CN | claimed |
| EP-2288652-B1 | PREPARATION FOR INITIATING RADICAL REACTIONS | UNITED INITIATORS GMBH & CO KG (DE) | 2012-09-19 | — | — | EP | claimed |
| US-20110272628-A1 | Preparation For Initiating Radical Reactions | UNITED INITIATORS GMBH (DE) | 2011-11-10 | — | — | US | claimed |
| EP-2288652-A1 | PREPARATION FOR INITIATING RADICAL REACTIONS | United Initiators GmbH & Co. KG (DE) | 2011-03-02 | — | — | EP | claimed |
| WO-2009146916-A1 | PREPARATION FOR INITIATING RADICAL REACTIONS | UNITED INITIATORS GMBH & CO. KG (DE) | 2009-12-10 | — | — | WO | claimed |
| EP-2130858-A1 | Preparations to initiate radical reactions | Degussa Initiators GmbH & Co. KG (DE) | 2009-12-09 | — | — | EP | claimed |
| US-5210313-A | Friedel crafts aryloylation of 1,4-dichlorobenzene and Lewis acids | MAXDEM INCORPORATED (US) | 1993-05-11 | — | — | US | claimed |
| US-20250313574-A1 | SIALIC ACID DERIVATIVES AND METHODS OF USING SAME | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2025-10-09 | — | — | US | disclosed |
| WO-2025098545-A1 | NUCLEOSIDE DERIVATIVES AS ANTIVIRAL AGENTS AGAINST CORONAVIRUSES | USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V. V. I. (CZ) | 2025-05-15 | — | — | WO | disclosed |
| EP-4553080-A1 | NUCLEOSIDE DERIVATIVES AS ANTIVIRAL AGENTS AGAINST CORONAVIRUSES | Ustav Organicke Chemie a Biochemie AV CR, v.v.i. (CZ) | 2025-05-14 | — | — | EP | disclosed |
| EP-4536653-A2 | SIALIC ACID DERIVATIVES AND METHODS OF USING SAME | Eisai R&D Management Co., Ltd. (JP) | 2025-04-16 | — | — | EP | disclosed |
| CN-117924279-B | MELK inhibitor and application thereof | 中山大学 | 2024-07-16 | — | — | CN | disclosed |
| US-4187230-A | Preparation of 5-aroyl-pyrrole compounds | ETHYL CORPORATION (US) | 1980-02-05 | — | — | US | disclosed |
| US-4176113-A | ANTRAQUINONE DYES | CIBA-GEIGY CORPORATION (US) | 1979-11-27 | — | — | US | disclosed |
| US-4138581-A | BRONCHODILATOR AGENTS, ADRENERGIC STIMULANTS | STERLING DRUGS INC. (US) | 1979-02-06 | — | — | US | disclosed |
| US-4004008-A | ANTISPASMODIC, VASODILATION | ROTTA RESEARCH LABORATORIUM S.P.A. (IT) | 1977-01-18 | — | — | US | disclosed |
| US-4000307-A | HYPOLIPIDEMIC | SANDOZ, INC. (US) | 1976-12-28 | — | — | US | disclosed |
| US-3952012-A | MULTISTAGE | MCNEIL LABORATORIES, INCORPORATED (US) | 1976-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250313574-A1 | SIALIC ACID DERIVATIVES AND METHODS OF USING SAME | NEU1, NEU2, NEU4 | SMN1; SMN2 301/4885CES2 775/4885CES1 1386/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.