Known targets — ChEMBL curated mechanism
CHRM1CHRM2CHRM3CHRM4CHRM5SLC6A2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Benzyl Viologen. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.69 |
| ▸ | RAB9A | P51151 | 1/20 | 0.69 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CHKA | P35790 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8863313 | 0.91 | ALDH1A1 (0.55) | ALDH1A1KDM4ERAB9AATMBCHE | |
| SCHEMBL146006 | 0.85 | ALDH1A1 (0.50) | ALDH1A1KDM4ERAB9AATMBCHE | |
| SCHEMBL11398694 | 0.85 | ALDH1A1 (0.50) | ALDH1A1KDM4ERAB9AATMBCHE | |
| SCHEMBL7621560 | 0.84 | KDM4E (0.46) | ALDH1A1KDM4ERAB9AATMBCHE | |
| SCHEMBL9241422 | 0.81 | LMNA (0.47) | ALDH1A1KDM4ERAB9ABCHEACHE | |
| SCHEMBL10553726 | 0.81 | CHKA (0.47) | ALDH1A1KDM4ERAB9ABCHEACHE | |
| SCHEMBL4088224 | 0.78 | TERT (0.42) | ALDH1A1KDM4ERAB9ACYP1A2CYP3A4 | |
| SCHEMBL6514943 | 0.78 | LMNA (0.43) | ALDH1A1ATMBCHEACHECA12 | |
| SCHEMBL8298734 | 0.77 | ACHE (0.47) | ALDH1A1KDM4EBCHEACHEL3MBTL1 | |
| SCHEMBL144741 | 0.77 | LMNA (0.44) | ALDH1A1KDM4ERAB9ACA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7500895-B2 | Patterned substrate, electro-optical device, and method for manufacturing an electro-optical device | SEIKO EPSON CORPORATION (JP) | 2009-03-10 | — | — | US | disclosed |
| US-20060127563-A1 | Patterned substrate, electro-optical device, and method for manufacturing an electro-optical device | SEIKO EPSON CORPORATION (JP) | 2006-06-15 | — | — | US | disclosed |