Known targets — ChEMBL curated mechanism
CHRM1CHRM2CHRM3CHRM4CHRM5SLC6A2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL144741 | 0.93 | LMNA (0.44) | ALDH1A1KDM4ERAB9ALMNAHTT | |
| Sulfuric Acid SCHEMBL141655 | 0.86 | LMNA (0.47) | ALDH1A1KDM4ERAB9ALMNAHTT | |
| Sulfuric Acid SCHEMBL141656 | 0.86 | LMNA (0.47) | ALDH1A1KDM4ERAB9ALMNAHTT | |
| Benzyl Viologen SCHEMBL4078032 | 0.85 | ALDH1A1 (0.69) | ALDH1A1KDM4ERAB9ALMNAHTT | |
| SCHEMBL8863313 | 0.85 | ALDH1A1 (0.55) | ALDH1A1KDM4ERAB9ALMNAHTT | |
| P-Cresol SCHEMBL1713061 | 0.84 | ALDH1A1 (0.55) | ALDH1A1KDM4ERAB9ALMNAHTT | |
| SCHEMBL736568 | 0.83 | LMNA (0.56) | ALDH1A1KDM4ERAB9ALMNAHTT | |
| SCHEMBL21837231 | 0.82 | RECQL (0.40) | ALDH1A1KDM4ERAB9ALMNAHTT | |
| SCHEMBL143552 | 0.82 | MAPT (0.46) | ALDH1A1KDM4ERAB9ALMNAHTT | |
| Bromide SCHEMBL140800 | 0.82 | LMNA (0.55) | ALDH1A1KDM4ERAB9ALMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2263642-B1 | Colouring bleaches | HENKEL AG & CO KGAA (DE) | 2020-04-15 | — | — | EP | disclosed |
| EP-2306963-B1 | MATTING ADDITIVE FOR BLEACHING | HENKEL AG & CO KGAA (DE) | 2018-03-28 | — | — | EP | disclosed |
| US-9693937-B2 | Foil applicator | HENKEL AG & CO. KGAA (DE) | 2017-07-04 | — | — | US | disclosed |
| US-20150174019-A1 | FOIL APPLICATOR | HENKEL AG & CO. KGAA (DE) | 2015-06-25 | — | — | US | disclosed |
| EP-2427247-B1 | FOIL APPLICATOR | HENKEL AG & CO KGAA (DE) | 2013-12-18 | — | — | EP | disclosed |
| US-8137412-B2 | Bleaching with concomitant hair tonicizing | HENKEL AG & CO. KGAA (DE) | 2012-03-20 | — | — | US | disclosed |
| EP-2427247-A2 | FOIL APPLICATOR | Henkel AG & Co. KGaA (DE) | 2012-03-14 | — | — | EP | disclosed |
| US-20120055500-A1 | Foil Applicator | HENKEL AG & CO. KGAA (DE) | 2012-03-08 | — | — | US | disclosed |
| US-20110232669-A1 | Bleaching with Concomitant Hair Tonicizing | HENKEL AG & CO. KGAA (DE) | 2011-09-29 | — | — | US | disclosed |
| US-8025704-B2 | Matting additive for blond hair dyeing | HENKEL AG & CO. KGAA (DE) | 2011-09-27 | — | — | US | disclosed |
| US-7981166-B2 | Bleaching agent having cationic acyl pyridinium derivatives, co-bleaching activators and hydrogen peroxide | HENKEL AG & CO. KGAA (DE) | 2011-07-19 | — | — | US | disclosed |
| US-20110126361-A1 | Matting Additive for Blond Hair Dyeing | MANNECK HARTMUT | 2011-06-02 | — | — | US | disclosed |
| EP-2306963-A1 | MATTING ADDITIVE FOR BLOND HAIR DYING | Henkel AG & Co. KGaA (DE) | 2011-04-13 | — | — | EP | disclosed |
| US-20110047712-A1 | BLEACHING AGENT HAVING CATIONIC ACYL PYRIDINIUM DERATIVES, CO-BLEACHING ACTIVATORS AND HYDROGEN PEROXIDE | HENKEL AG & CO. KGAA (DE) | 2011-03-03 | — | — | US | disclosed |
| EP-2263642-A2 | Colouring bleaches | Henkel AG & Co. KGaA (DE) | 2010-12-22 | — | — | EP | disclosed |
| WO-2010127902-A2 | FOIL APPLICATOR | HENKEL AG & CO. KGAA (DE) | 2010-11-11 | — | — | WO | disclosed |
| WO-2010015441-A1 | MATTING ADDITIVE FOR BLOND HAIR DYING | HENKEL AG & CO. KGAA (DE) | 2010-02-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110047712-A1 | BLEACHING AGENT HAVING CATIONIC ACYL PYRIDINIUM DERATIVES, CO-BLEACHING ACTIVATORS AND HYDROGEN PEROXIDE | F12, KRT18, H1-3 | ALDH1A1 980/4885KDM4E 2827/4885RAB9A 2260/4885 |
| US-20110126361-A1 | Matting Additive for Blond Hair Dyeing | LDHB, HMBS, HBB | ALDH1A1 2121/4885KDM4E 1253/4885RAB9A 2686/4885 |
| US-20110232669-A1 | Bleaching with Concomitant Hair Tonicizing | KRT18, KAT7, KAT2B | ALDH1A1 628/4885KDM4E 1089/4885RAB9A 3602/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.