Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | G6PC1 | P35575 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | FURIN | P09958 | 1/20 | 0.30 |
| ▸ | EPOR | P19235 | 1/20 | 0.30 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4074955 | 0.73 | MEN1 (0.41) | PTGS2LMNAMEN1MAPTKMT2A | |
| SCHEMBL720917 | 0.65 | G6PC1 (0.49) | LMNAMEN1MAPTKMT2AG6PC1 | |
| SCHEMBL720915 | 0.65 | G6PC1 (0.49) | LMNAMEN1MAPTKMT2AG6PC1 | |
| SCHEMBL8241465 | 0.65 | ALDH1A1 (0.48) | PTGS2MAPTKMT2ATP53TDP1 | |
| Urea SCHEMBL29001189 | 0.65 | TDP1 (0.52) | PTGS2MEN1KMT2ATP53TDP1 | |
| SCHEMBL21881 | 0.64 | TDP1 (0.67) | PTGS2TP53TDP1ALDH1A1TSHR | |
| SCHEMBL13569016 | 0.63 | GFER (0.49) | LMNAMEN1KMT2ATDP1ALDH1A1 | |
| Styrene SCHEMBL9639895 | 0.62 | ALDH1A1 (0.78) | PTGS2LMNATP53TDP1FAAH | |
| SCHEMBL11957623 | 0.62 | TP53 (0.48) | PTGS2TP53TDP1ALDH1A1TSHR | |
| Ammonia Solution, Strong SCHEMBL31335086 | 0.62 | TDP1 (0.64) | PTGS2MEN1MAPTKMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009155362-A1 | SMALL MOLECULE HEMATOPOIETIC GROWTH FACTOR MIMETIC COMPOUNDS AND THEIR USES | LIGAND PHARMACEUTICALS INC. (US) | 2009-12-23 | — | — | WO | disclosed |