Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4078640 | 0.85 | CYP11B1 (0.31) | — | |
| Hydrochloric Acid SCHEMBL7643733 | 0.84 | ALDH1A1 (0.36) | CYP3A4HPGDTSHRMAPK1CASP1 | |
| Hydrochloric Acid SCHEMBL7807249 | 0.79 | CYP1A2 (0.34) | — | |
| Hydrochloric Acid SCHEMBL7643736 | 0.75 | CYP1A2 (0.33) | CYP3A4HPGDTSHRMAPK1CASP1 | |
| Hydrochloric Acid SCHEMBL7807224 | 0.74 | PTPN1 (0.35) | HPGDTSHRMAPK1RAB9AATM | |
| Hydrochloric Acid SCHEMBL8169170 | 0.73 | PSMB5 (0.32) | — | |
| Hydrochloric Acid SCHEMBL4078644 | 0.73 | HTR6 (0.34) | — | |
| Hydrochloric Acid SCHEMBL8158883 | 0.71 | TLR8 (0.32) | — | |
| Hydrochloric Acid SCHEMBL6898339 | 0.70 | CYP1A2 (0.41) | — | |
| Hydrochloric Acid SCHEMBL7196886 | 0.69 | CYP1A2 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010007009-A1 | Transition metal catalyzed polymerization of olefinic monomers in a water-containing polymerization medium | BASF AKTIENGESELLSCHAFT (DE) | 2001-07-05 | — | — | US | disclosed |